Involvement of H2O2 production in cisplatin-induced nephrotoxicity

Biochemical and Biophysical Research Communications
Y TsutsumishitaM Niwa

Abstract

The purpose of this study was to elucidate the involvement of H2O2 production in cisplatin-induced nephrotoxicity. The S3 cells were more sensitive than OMCT cells in cell viability and H2O2 production during cisplatin treatment. The cytotoxicity and H2O2 production induced by cisplatin were terminated by treatment with catalase. In conclusion, we emphasize the importance of the hydroxy radical in cisplatin nephrotoxicity.

References

Jan 1, 1989·Cancer Chemotherapy and Pharmacology·G Daugaard, U Abildgaard

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Citations

Aug 25, 2012·Journal of Toxicology·Damian G DeavallRuth Roberts
Oct 16, 2012·Experimental and Molecular Pathology·Paul B YaffeDavid W Hoskin
Jan 18, 2006·Journal of Pharmacological Sciences·Yoshiko KawaiMunekazu Gemba
Dec 8, 2009·Journal of Pharmacological Sciences·Yoshiko KawaiMunekazu Gemba
Jun 11, 2008·The American Journal of Chinese Medicine·Fumie HisamuraIsao Matsui-Yuasa
Dec 8, 2007·Toxicology Letters·Yolanda I ChirinoJosé Pedraza-Chaverri
Apr 9, 2019·The Journal of Pharmacy and Pharmacology·Swati KaushikJagriti Bhatia
Dec 31, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Hua ZhouAkira Hishida
Jun 15, 2017·Cancer Chemotherapy and Pharmacology·Júlia Coelho França QuintanilhaPatricia Moriel
May 17, 2019·Journal of Toxicologic Pathology·Ayaka SasakiKazuhiko Suzuki
Oct 31, 2020·Cutaneous and Ocular Toxicology·Ibrahim AhiskaliHalis Suleyman
Sep 26, 2020·Canadian Journal of Physiology and Pharmacology·Katarina MihajlovicSlobodan Novokmet
Apr 28, 2021·Experimental Gerontology·Mohammad AlthubitiAbdullatif Babakr
Feb 17, 2001·Biochemical and Biophysical Research Communications·H S KimC H Choi
Dec 1, 2001·Journal of the American Society of Nephrology : JASN·Christopher A DavisAnupam Agarwal
Jul 28, 2004·Biochimica Et Biophysica Acta·Agnieszka StachurskaBarbara Grzelakowska-Sztabert
Nov 7, 2008·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·Yolanda I Chirino, José Pedraza-Chaverri
Oct 14, 2011·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Laila A RashedHala M Soliman

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