Involvement of host factors in transcription from baculovirus very late promoters -- a review

Gene
S E HasnainC A Azim

Abstract

The baculovirus expression vector system has emerged as the system of choice for the expression of a number of heterologous genes of both prokaryotic and eukaryotic origin. This system utilizes the baculovirus very late, hyperactive polyhedrin and p10 promoters to drive the transcription of foreign genes. Regulation of transcription from these promoters is presently not well understood even though a number of viral gene products that may be important for transcription have been identified. Fresh insight into host-virus interactions during baculovirus pathogenesis is now offered by the identification of insect host factors that interact with transcriptionally essential motifs of these promoters as well as cis-acting enhancer-like elements upstream from the promoter.

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Citations

May 8, 2003·Journal of Biosciences·Seyed E HasnainM Krishnaveni
Feb 18, 2009·Archives of Virology·M Senthil KumarMurali Dharan Bashyam
Apr 13, 2006·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Graham SinclairFrancis Y M Choy
May 17, 2008·Virus Genes·Guohui LiXunzhang Wang
May 1, 2012·Protein Expression and Purification·Rebecca L BradingEileen J McCall
Sep 11, 2012·Journal of Basic Microbiology·Hongxing ShenXiaoyong Liu
Feb 5, 2008·Molecular Biology Reports·Jun-Qing GeChuan-Xi Zhang
Feb 3, 2000·Molecular Genetics and Metabolism·K J NorrgardB Wolf

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