Involvement of noncoding RNAs in epigenetic modifications of esophageal cancer

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
Yuhang XiaoYong Zhou

Abstract

Esophageal cancer (EC) is a serious digestive malignancy and is a leading cause of cancer-related mortality. Apart from genetic mutations, many epigenetic alterations including DNA methylation and histone modifications associated with chromatin remodeling have been identified in the regulation of gene expression in EC. Recently, noncoding RNAs, and mainly lncRNAs and miRNAs, have been revealed to be involved in the epigenetic regulation of EC. In this review, we focus on describing new insights on epigenetic processes associated with noncoding RNAs, which have been characterized to be responsible for the development and progression of EC.

Citations

Mar 14, 2020·Molecular Cancer·Kaisheng LiuZhe-Sheng Chen
Oct 13, 2020·Biochemistry. Biokhimii︠a︡·M V NemtsovaA A Zamyatnin
Apr 26, 2021·Drug Discovery Today·Ganji Purnachandra NagarajuSarfraz Ahmad
Aug 3, 2021·Frontiers in Cell and Developmental Biology·Lijun WangXuesong Jiang

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