Involvement of S2 episomal sequences in the generation of NCS4 deletion mutation in maize mitochondria

Developmental Genetics
Kathleen J NewtonS J Gabay-Laughnan

Abstract

Cytoplasmic male sterility (CMS) and the abnormal-growth, nochromosomal stripe (NCS) phenotypes are cytoplasmically determined traits in plants. Mitochondrial DNA rearrangements involving short repeats appear to be responsible for the production of CMS reversions to fertility and NCS mutations. NCS4, a new mutant of maize CMS-S, exhibits both abnormal growth and male fertility. This mutant is unique because both mutations occurred within the same plant. Free S1 and S2 episomes normally found in CMS-S mitochondria have been lost from NCS4 plants. An S2 sequence has recombined aberrantly with a ribosomal protein coding region, rps3/rpl16. One end of the S2 sequence and the 5' end of the rps3/rpl16 transcription unit are absent from the NCS4 recombinant genome. Loss of mitochondrial ribosomal protein function is lethal; therefore, NCS4 plants are heteroplasmic for the rps3 deletion. Loss of S sequences from CMS-S mitochondria is not lethal and plants regain pollen function. Thus, although NCS4 plants have very abnormal plant phenotypes, they are male-fertile.

References

Jan 1, 1991·Annual Review of Genetics·M R Hanson
Jan 1, 1986·Methods in Enzymology·D B Stern, K J Newton
Dec 1, 1993·PCR Methods and Applications·J R MarienfeldK J Newton
Jun 1, 1995·Trends in Genetics : TIG·C FauronB Moore
Apr 1, 1993·Trends in Genetics : TIG·D C Wallace
Jul 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·C S Levings, R R Sederoff
Oct 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·K J Newton, E H Coe
Oct 1, 1988·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·I D SmallC J Leaver
Jun 1, 1985·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·A E OroV Walbot
Jul 1, 1986·Plant Molecular Biology·P L Traynor, C S Levings

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Citations

Jul 16, 2008·Plant & Cell Physiology·Sota Fujii, Kinya Toriyama
Feb 1, 2005·Plant Physiology·Evgeny V KuzminKathleen J Newton
Dec 7, 2002·The Plant Cell·Olga V KarpovaKathleen J Newton
May 1, 2007·The Plant Cell·Vikas ShedgeSally A Mackenzie
Dec 7, 2007·Journal of Molecular Biology·Magalie UyttewaalPhilippe Giegé
Feb 27, 2007·Mitochondrion·David M Rhoads, Chalivendra C Subbaiah
Apr 3, 2016·Free Radical Biology & Medicine·Katie L LiberatoreShahryar F Kianian
Oct 1, 2013·Biochimie·José M GualbertoAndré Dietrich
Sep 3, 2013·Biochimie·Catherine Colas des Francs-Small, Ian Small
Apr 4, 2008·Molecular & Cellular Proteomics : MCP·Chun Pong LeeA Harvey Millar
Jan 1, 1996·Developmental Genetics·M L King
Mar 16, 2004·The Journal of Biological Chemistry·Evgeny V KuzminKathleen J Newton
Dec 11, 2007·Mitochondrion·Tomohiko Kubo, Kathleen J Newton

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