Involvement of the anterior urethra in male patients with transitional cell-carcinoma of the bladder undergoing radical cystectomy with simultaneous urethrectomy

Japanese Journal of Clinical Oncology
K TobisuT Kakizoe

Abstract

Histological tumor extension into the prostate, urethra and ureters was examined in 52 specimens obtained by cystourethrectomy for transitional cell carcinoma of the bladder with one or more risk factors for urethral involvement. In four (21.1%) of 19 patients with diffuse carcinoma in situ in the bladder extending to the internal urethral orifice and prostatic urethra, the anterior urethra was affected by transitional cell carcinoma, including one specimen with invasion into the corpus spongiosum. However, none of 33 patients without these findings had synchronous anterior urethral transitional cell carcinoma involvement. It is recommended that patients with diffuse carcinoma in situ extending into the prostatic urethra undergo careful preoperative assessment of the anterior urethra before cystectomy. In other cases, the anterior urethra can be preserved and used for orthotopic neobladder replacement.

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Citations

Oct 24, 2006·International Journal of Clinical Oncology·Kenichi Tobisu
Jun 21, 2002·European Urology·Arnulf StenzlHermann Rogatsch
Sep 8, 1998·Japanese Journal of Clinical Oncology·T Kakizoe, K Tobisu
Aug 31, 2004·Japanese Journal of Clinical Oncology·Taiji TsukamotoNaoya Masumori
Aug 3, 2010·The Urologic Clinics of North America·Shawn E White, S Bruce Malkowicz
Feb 7, 2007·Urology·Juan PalouPierfranco Bassi
May 3, 2005·The Urologic Clinics of North America·Peter E Clark, M Craig Hall
Jul 19, 2005·World Journal of Surgical Oncology·M Hammad AtherOrhun Sinanoglu
Dec 4, 2010·The Kaohsiung Journal of Medical Sciences·Osman ErgünIbrahim Metin Ciriş

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