Involvement of the cerebellum in classical fear conditioning in goldfish

Behavioural Brain Research
Masayuki YoshidaKazumasa Uematsu

Abstract

To investigate the emotional role of the cerebellum of fish, we conducted experiments examining effects of cerebellar manipulations on fear-related classical heart rate conditioning in goldfish. We performed total ablation of the corpus cerebelli to examine the effect of irreversible effects. We also performed localized cooling of the corpus cerebelli, in place of the ablation, for reversible inactivation of the cerebellar function. Both the cardiac arousal response to the first presentation of the conditioned stimulus and the cardiac reflex to the aversive unconditioned stimulus were not impaired by the ablation or cooling of the corpus cerebelli. On the other hand, inactivation of cerebellar function severely impaired the acquisition of a conditioned cardiac response in the fear-related conditioning. In addition, localized cooling of the corpus cerebelli reversibly suppressed the expression of established conditioned response. We suggest that the cerebellum of fish is not only being a motor coordination center but also is involved in emotional learning.

References

Dec 1, 1979·Physiology & Behavior·B S KappJ R Haselton
Feb 1, 1974·Experimental Neurology·J B Overmier, G E Savage
Jun 1, 1969·Journal of Comparative and Physiological Psychology·J B Overmier, P F Curnow
Jun 1, 1982·Journal of Comparative and Physiological Psychology·P R Laming, P Ennis
Sep 1, 1994·Journal of Neurophysiology·A M PastorR Baker
Jun 9, 2000·Annual Review of Neuroscience·J E LeDoux
Feb 12, 2002·Nature Reviews. Neuroscience·Javier F MedinaJoseph E LeDoux
May 30, 2002·Proceedings of the National Academy of Sciences of the United States of America·Benedetto SacchettiCorrado Bucherelli
Sep 11, 2002·Brain, Behavior and Evolution·Curtis C Bell
Sep 20, 2002·Brain, Behavior and Evolution·Takanori IkenagaKazumasa Uematsu
Nov 29, 2002·Brain, Behavior and Evolution·B L RobertsD H Paul
Jun 12, 2004·Behavioral and Cognitive Neuroscience Reviews·Jeffrey B Rosen

❮ Previous
Next ❯

Citations

Sep 24, 2005·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Gabriela Hermitte, Héctor Maldonado
Aug 21, 2013·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Susanne SchwarzeVera Schluessel
Sep 30, 2005·Development Genes and Evolution·Mayumi TsuchimotoTatsuhiko Kadowaki
Feb 6, 2008·Zebrafish·Cosme SalasFernando Rodríguez
Dec 21, 2007·Nuclear Medicine Communications·Luca BurroniAngelo G Vattimo
May 24, 2007·Brain, Behavior and Evolution·Noritaka MatsumotoKazumasa Uematsu
Sep 1, 2009·Zoological Science·Masayuki YoshidaTakao Shima
May 11, 2010·Physiology & Behavior·Ana Burnovicz, Gabriela Hermitte
Jun 1, 2010·Behavioural Brain Research·Caio MaximinoAmauri Gouveia
Mar 3, 2007·The European Journal of Neuroscience·Konstantinos Ampatzis, Catherine R Dermon
Feb 27, 2010·The Journal of Comparative Neurology·Konstantinos Ampatzis, Catherine R Dermon
Nov 2, 2012·Behavioral and Brain Functions : BBF·Masayuki Yoshida, Hiroki Kondo
May 5, 2009·Neuroscience·B SacchettiP Strata
Nov 5, 2013·Behavioural Brain Research·Emilio DuránCosme Salas
May 25, 2005·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Benedetto SacchettiPiergiorgio Strata
May 10, 2019·Frontiers in Neural Circuits·Ryuji DohakuMasahiko Hibi
Nov 13, 2019·Scientific Reports·Rupali SharmaDiego Iacono

❮ Previous
Next ❯

Related Concepts

Related Feeds

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.

Bradyarrhythmias

Bradyarrhythmias are slow heart rates. Symptoms may include syncope, dizziness, fatigure, shortness of breath, and chest pains. Find the latest research on bradyarrhythmias here.