Involvement of two latex-clearing proteins during rubber degradation and insights into the subsequent degradation pathway revealed by the genome sequence of Gordonia polyisoprenivorans strain VH2.

Applied and Environmental Microbiology
Sebastian HiesslA Steinbüchel

Abstract

The increasing production of synthetic and natural poly(cis-1,4-isoprene) rubber leads to huge challenges in waste management. Only a few bacteria are known to degrade rubber, and little is known about the mechanism of microbial rubber degradation. The genome of Gordonia polyisoprenivorans strain VH2, which is one of the most effective rubber-degrading bacteria, was sequenced and annotated to elucidate the degradation pathway and other features of this actinomycete. The genome consists of a circular chromosome of 5,669,805 bp and a circular plasmid of 174,494 bp with average GC contents of 67.0% and 65.7%, respectively. It contains 5,110 putative protein-coding sequences, including many candidate genes responsible for rubber degradation and other biotechnically relevant pathways. Furthermore, we detected two homologues of a latex-clearing protein, which is supposed to be a key enzyme in rubber degradation. The deletion of these two genes for the first time revealed clear evidence that latex-clearing protein is essential for the microbial utilization of rubber. Based on the genome sequence, we predict a pathway for the microbial degradation of rubber which is supported by previous and current data on transposon mutagenesis, dele...Continue Reading

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Citations

Aug 28, 2012·Applied and Environmental Microbiology·Hao-Ping ChenLindsay D Eltis
Oct 16, 2012·Applied and Environmental Microbiology·Christian FleigeAlexander Steinbüchel
Dec 12, 2012·Applied and Environmental Microbiology·Quan LuoAlexander Steinbüchel
Aug 29, 2013·Environmental Microbiology·Quan LuoAlexander Steinbüchel
Jul 21, 2016·Nefrología : publicación oficial de la Sociedad Española Nefrologia·Laura Salanova VillanuevaBorja Quiroga
Jan 24, 2017·Bioscience, Biotechnology, and Biochemistry·Daisuke KasaiMasao Fukuda
Jul 12, 2017·Microbial Biotechnology·Wolf RötherDieter Jendrossek
Apr 1, 2018·Biotechnology Progress·R AndlerA Steinbüchel
Dec 26, 2017·Critical Reviews in Microbiology·Harshada SowaniSmita Zinjarde
May 14, 2017·Applied and Environmental Microbiology·Jakob BirkeDieter Jendrossek
Aug 13, 2013·Applied and Environmental Microbiology·Jakob BirkeDieter Jendrossek
Jul 26, 2013·Journal of Clinical Microbiology·Poornima RamananNancy L Wengenack
Jun 15, 2014·Applied and Environmental Microbiology·Sebastian HiesslAlexander Steinbüchel
Apr 22, 2014·Applied and Environmental Microbiology·Quan LuoAlexander Steinbüchel
Oct 30, 2016·Applied and Environmental Microbiology·Wolf RötherDieter Jendrossek
Nov 1, 2018·Applied Microbiology and Biotechnology·Dieter Jendrossek, Jakob Birke
Jan 11, 2019·Microbiology·Sylvia OetermannAlexander Steinbüchel
May 24, 2019·Applied Microbiology and Biotechnology·Anna CoenenAlexander Steinbüchel
Aug 24, 2019·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Stefania Pegorin BragaRenata Castiglioni Pascon
Sep 6, 2019·Applied Microbiology and Biotechnology·Jakob Birke, Dieter Jendrossek
Mar 3, 2020·Bioscience, Biotechnology, and Biochemistry·Daisuke Kasai
Jun 14, 2017·BMC Infectious Diseases·Xiurong DingJinli Lou
Sep 15, 2018·Applied Microbiology and Biotechnology·Jakob BirkeDieter Jendrossek
Jul 19, 2020·Applied Microbiology and Biotechnology·Namiko GibuDaisuke Kasai
Sep 29, 2017·Applied Microbiology and Biotechnology·Robin VivodAlexander Steinbüchel
Jul 3, 2021·Polymers·Ann Anni BasikKumar Sudesh
Sep 17, 2021·Macromolecular Bioscience·Franciela Arenhart Soares, Alexander Steinbüchel
Nov 5, 2021·Frontiers in Bioengineering and Biotechnology·R AndlerM Salazar-Viedma

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