Iodine deficiency during infancy and early childhood in Belgium: does it pose a risk to brain development?

European Journal of Pediatrics
François DelangeF Vertongen

Abstract

Iodine deficiency is well documented in Belgium in adults including pregnant women, adolescents, schoolchildren, and neonates, but no data are available in the age group 6 months-3 years. We investigated the status of iodine nutrition in 111 healthy subjects in this age group in an attempt to evaluate the risk of brain damage due to iodine deficiency in Belgium. In 244 causal urine samples collected in these subjects, the median concentration of iodine was 101 micrograms/l vs 180-220 micrograms/l under normal conditions. The daily supplementation of the subjects with a physiological dose of 90 micrograms iodine was followed by a slow and progressive increase of urinary iodine, which reached a normal level only after a delay of about 30 weeks of therapy. This observation suggests that part of the supplement of iodine offered to the children was stored in their thyroid glands until the iodine content of the gland had reverted to normal, reflecting the state of hyperavidity of the thyroid for iodide characteristic of iodine deficiency. In conclusion, infants and young children in Belgium are as iodine deficient as all other age groups of the population and, consequently, are at risk of brain damage. This works further illustrates ...Continue Reading

Citations

Aug 29, 2003·Public Health Nutrition·Laura Rossi, Francesco Branca
Aug 24, 2004·Archives of Disease in Childhood. Fetal and Neonatal Edition·M S KibirigeH T Delves
Mar 2, 2006·Annals of Nutrition & Metabolism·P DlouhýM Andel
May 11, 2013·Public Health Nutrition·Morven I F A LeanEmilie Combet
Feb 23, 2010·Best Practice & Research. Clinical Endocrinology & Metabolism·Juliawati UntoroWerner Schultink
Jul 22, 2008·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·G PouesselD Turck
May 31, 2012·Maternal & Child Nutrition·Sheila SkeaffShao Jia Zhou
Mar 31, 2005·Nutrition·Sheila A SkeaffChristine D Thomson
May 8, 2015·Thyroid : Official Journal of the American Thyroid Association·Ashwini Kumar NepalMichael Bruce Zimmermann
May 11, 2005·The American Journal of Clinical Nutrition·Lindsay H Allen
Nov 30, 2019·Pediatric Gastroenterology, Hepatology & Nutrition·Yvan VandenplasSulaiman Alsaad
Jul 29, 2016·The American Journal of Clinical Nutrition·Susanne DoldMaria Andersson
Jun 3, 2021·Cancers·Gabriella SchieraItalia Di Liegro
Nov 19, 2021·Endocrine Reviews·Maria Andersson, Christian P Braegger

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