Ion Distribution Profiling in an Ion Mobility Spectrometer by Laser-Induced Fluorescence

Analytical Chemistry
Kaitai GuoXiaohao Wang

Abstract

Measuring the ion distribution pattern in a drift tube under atmospheric pressure is very useful for studies of ion motion and design of ion mobility spectrometers (IMS); however, no mature method is available for conducting such measurements at present. We propose a simple and low-cost technique for profiling the two-dimensional ion distribution in any cross section of a drift tube. Similar to particle-image velocimetry, we first send sample ions with fluorescence properties into the drift tube and use a receiving plate to collect and accumulate them. Then, the receiving plate is illuminated by exciting light, and the ion distribution appears as a fluorescence image. In this study, Rhodamine 6G was selected as a typical fluorescence-tracer particle. Electrospray ionization (ESI) was chosen as an ionization source to keep the fluorophore undamaged. A plasma-cleaned coverslip was placed at the detection position as a receiving plate. When a layer of ions was collected, the slide was placed under the exciting light with a wavelength of 473 nm. A camera with a 490 nm high-pass light filter was used to capture the fluorescence image representing the ion distribution. The measured-ion detection efficiency of the method was 156 ion/d...Continue Reading

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