Ion sources for mass spectrometric identification and imaging of molecular species

Natural Product Reports
Chhavi Bhardwaj, Luke Hanley

Abstract

Covering: 2013 The ability to transfer molecular species to the gas phase and ionize them is central to the study of natural products and other molecular species by mass spectrometry (MS). MS-based strategies in natural products have focused on a few established ion sources, such as electron impact and electrospray ionization. However, a variety of other ion sources are either currently in use to evaluate natural products or show significant future promise. This review discusses these various ion sources in the context of other articles in this special issue, but is also applicable to other fields of analysis, including materials science. Ion sources are grouped based on the current understanding of their predominant ion formation mechanisms. This broad overview groups ion sources into the following categories: electron ionization and single photon ionization; chemical ionization-like and plasma-based; electrospray ionization; and, laser desorption-based. Laser desorption-based methods are emphasized with specific examples given for laser desorption postionization sources and their use in the analysis of intact microbial biofilms. Brief consideration is given to the choice of ion source for various sample types and analyses, in...Continue Reading

References

Jan 8, 1999·Journal of the American Society for Mass Spectrometry·T ShaharA Amirav
Jul 17, 1999·Journal of Mass Spectrometry : JMS·L HanleyJ L Trevor
Nov 18, 2000·Analytical Chemistry·V V LaikoR J Cotter
Jan 8, 2004·Analytical Chemistry·Jamal I BerryNicholas Winograd
May 1, 2004·Analytical Chemistry·Jamie E ElsilaRichard N Zare
Nov 3, 2004·Journal of the American Society for Mass Spectrometry·Jack A Syage
Nov 13, 2004·Analytical Chemistry·Tiina J KauppilaRisto Kostiainen
Feb 22, 2005·Biomaterials·Yaoming LiuRobert J Gordon
Apr 14, 2005·Journal of the American Chemical Society·John A McLeanDavid H Russell
Feb 2, 2006·Analytical Chemistry·A F Maarten AltelaarSander R Piersma
Apr 4, 2006·Analytical Chemistry·Timothy J Garrett, Richard A Yost
Oct 19, 2006·The Analyst·Richard Knochenmuss
Sep 7, 2007·Analytical Chemistry·Markus HaapalaRisto Kostiainen
Sep 18, 2007·Analytical and Bioanalytical Chemistry·Thomas Adam, Ralf Zimmermann
Oct 5, 2007·Analytical Chemistry·Alexander V ZinovevMichael J Pellin
Jan 30, 2008·Journal of Mass Spectrometry : JMS·Aviv AmiravAlexander B Fialkov
Jun 4, 2008·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Zhaoyang Chen, Akos Vertes
Oct 7, 2008·Investigative Ophthalmology & Visual Science·Hiroshi NakamuraDeepak P Edward
Jan 21, 2009·Analytical and Bioanalytical Chemistry·A WucherN Winograd
Feb 14, 2009·Chemical Reviews·Robert S BlakeAndrew M Ellis
Mar 13, 2009·Rapid Communications in Mass Spectrometry : RCM·J M WichmannA Lindinger
Mar 24, 2009·Analytical Chemistry·Oscar YanesGary Siuzdak
May 30, 2009·Analytical Chemistry·Luke Hanley, Ralf Zimmermann
Jun 25, 2009·Mass Spectrometry Reviews·Paul Kebarle, Udo H Verkerk
Jul 25, 2009·Mass Spectrometry Reviews·Thomas R CoveyBradley B Schneider
Oct 13, 2009·ACS Chemical Biology·Roland D Kersten, Pieter C Dorrestein
Oct 20, 2009·The Analyst·Zheng-Jiang ZhuRichard W Vachet
Feb 11, 2010·Journal of Mass Spectrometry : JMS·Artem AkhmetovLuke Hanley
Mar 10, 2010·Analytical Chemistry·Yves CoelloMarcos Dantus
Mar 13, 2010·Journal of Chromatography. a·Erika R Amstalden van HoveRon M A Heeren
May 14, 2010·Analytical Chemistry·Jennifer J D FitzgeraldAmy V Walker

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Citations

Jul 23, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Loïc BeckerPatrick Chaimbault
Feb 24, 2016·Frontiers in Plant Science·Yonghui DongPietro Franceschi
Apr 8, 2016·Journal of the American Society for Mass Spectrometry·Sandilya V B GarimellaRichard D Smith
Jun 7, 2015·Analytical and Bioanalytical Chemistry·Alena M RodriguezFrank Marí
Jun 21, 2017·Analytical Chemistry·Yeni P YungLuke Hanley
Jul 5, 2016·Natural Product Reports·Matthew T Henke, Neil L Kelleher
May 23, 2015·The Analyst·Tal Luzzatto-KnaanPieter C Dorrestein
Feb 21, 2019·Annual Review of Analytical Chemistry·Luke HanleyYeni P Yung
Dec 1, 2016·Current Protocols in Plant Biology·Manuela PeukertAndrea Matros
Dec 18, 2020·Clinica Chimica Acta; International Journal of Clinical Chemistry·Kenichi Tamama
Mar 4, 2021·Journal of the American Society for Mass Spectrometry·Michael J TaylorChristopher R Anderton
Sep 23, 2020·The Journal of Physical Chemistry Letters·Cornelius L PieterseLuke Hanley

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