PMID: 6025116Jun 23, 1967Paper

Ionic mechanism of cholinergic inhibition in molluscan neurons

Science
D J Chiarandini, H GERSCHENFELD

Abstract

Acetylcholine, the inhibitory transmitter to the so-called H-neurons of molluscs, produces its effect by increasing the permeability of the subsynaptic membrane to chloride ions. The change in permeability gives rise to a net influx of this anion, which hyperpolarizes the neuron. The presence of an outward pump of chloride ions is postulated to account for the required electrochemical gradient. The participation of potassium ions in this inhibitory phenomenon was not detected.

References

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Citations

Dec 13, 1973·Naunyn-Schmiedeberg's Archives of Pharmacology·J C Hancock
Jan 1, 1989·Neir̆ofiziologiia = Neurophysiology·A S Pivovarov, G N Saganelidze
Feb 1, 1971·Comparative Biochemistry and Physiology. A, Comparative Physiology·J R Zollman, H Gainer
Jan 1, 1989·Comparative Biochemistry and Physiology. A, Comparative Physiology·K A GreenG A Cottrell
Jan 1, 1978·Comparative Biochemistry and Physiology. C: Comparative Pharmacology·I McCance, R Werman
Jan 1, 1986·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·A J Bokisch, R J Walker
Sep 1, 1970·The Journal of General Physiology·J S McReynolds, A L Gorman
Nov 1, 1972·The Journal of General Physiology·J M Russell, A M Brown
Jan 1, 1980·Annals of the New York Academy of Sciences·J M Russell
Dec 7, 1973·Brain Research·M Stepita-KlaucoE Giacobini

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