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Ionic properties of the acetylcholine receptor in cultured rat myotubes

The Journal of General Physiology

Jun 1, 1975

A K Ritchie, D M Fambrough

PMID: 460

Abstract

The acetylcholine reversal potential (Er) of cultured rat myotubes is -3mV. When activated, the receptor is permeable to K+ and Na+, but not to Cl- ions. Measurement of Er in Tris+-substituted, Na-free medium also indicated a permeability to Tris+ ions. Unlike adult frog muscle the magn...read more

Mentioned in this Paper

Hydrogen-Ion Concentration
Culture Techniques
kappa-Bungarotoxin
Resting Potentials
Muscle
Potassium
Cholinergic Receptors
Sodium
Metazoa
Calcium
Paper Details
References
  • References11
  • Citations17
12

Ionic properties of the acetylcholine receptor in cultured rat myotubes

The Journal of General Physiology

Jun 1, 1975

A K Ritchie, D M Fambrough

PMID: 460

DOI:

Abstract

The acetylcholine reversal potential (Er) of cultured rat myotubes is -3mV. When activated, the receptor is permeable to K+ and Na+, but not to Cl- ions. Measurement of Er in Tris+-substituted, Na-free medium also indicated a permeability to Tris+ ions. Unlike adult frog muscle the magn...read more

Mentioned in this Paper

Hydrogen-Ion Concentration
Culture Techniques
kappa-Bungarotoxin
Resting Potentials
Muscle
Potassium
Cholinergic Receptors
Sodium
Metazoa
Calcium

Related Papers

Paper Details
References
  • References11
  • Citations17
12
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