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Ionic properties of the acetylcholine receptor in cultured rat myotubes

The Journal of General Physiology

Jun 1, 1975

A K Ritchie, Douglas M Fambrough

PMID: 460

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Abstract

The acetylcholine reversal potential (Er) of cultured rat myotubes is -3mV. When activated, the receptor is permeable to K+ and Na+, but not to Cl- ions. Measurement of Er in Tris+-substituted, Na-free medium also indicated a permeability to Tris+ ions. Unlike adult frog muscle the magn...read more

Mentioned in this Paper

Potassium
Decamethonium Compounds
Sodium
Metazoa
Cell Membrane Permeability
Calcium
Hydrogen-Ion Concentration
Culture Techniques
kappa-Bungarotoxin
Electrophysiology (Science)
Paper Details
References
    • References11
    • Citations13
    • References11
    • Citations13
  • Ionic properties of the acetylcholine receptor in cultured rat myotubes

    The Journal of General Physiology

    Jun 1, 1975

    A K Ritchie, Douglas M Fambrough

    PMID: 460

    DOI:

    Abstract

    The acetylcholine reversal potential (Er) of cultured rat myotubes is -3mV. When activated, the receptor is permeable to K+ and Na+, but not to Cl- ions. Measurement of Er in Tris+-substituted, Na-free medium also indicated a permeability to Tris+ ions. Unlike adult frog muscle the magn...read more

    Mentioned in this Paper

    Potassium
    Decamethonium Compounds
    Sodium
    Metazoa
    Cell Membrane Permeability

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    Paper Details
    References
    • References11
    • Citations13
    • References11
    • Citations13
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