PMID: 6164429Apr 1, 1981Paper

Ionized calcium in acute pancreatitis and its relationships with total calcium and serum lipase

The British Journal of Surgery
R S CrotonN B Roberts

Abstract

Serial measurements of serum amylase, lipase and ionized calcium were made in a prospective study of 17 patients with acute pancreatitis. The mean serum ionized calcium was significantly below the normal range for the first 24 h and had returned to normal after 48 h. There was no correlation between serum ionized calcium and paired calcium corrected for albumin during the first 36 h of the study, but they were correlated for the remainder of the investigation. Serum lipase and ionized calcium levels were just significantly correlated over the first 3 days (r = -0.44; t = 2.3; P less than 0.05; d.f. 22), but failed to reach correlation over the whole period of study (r = -0.34; t = 2.0; d.f. 31). These data establish a significant drop in directly measured ionized calcium early in an attack of pancreatitis, which is not seen in the paired corrected calcium values. Furthermore, the drop is correlated with serum lipase, although this is weak and other factors must be involved in the hypocalcaemia.

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Citations

May 16, 2003·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Paul Georg LankischAlbert B Lowenfels
Mar 1, 1994·The British Journal of Surgery·C McKayJ N Baxter
Dec 1, 1989·The British Journal of Surgery·P A ClavienA R Moossa
Jan 1, 1987·Scandinavian Journal of Gastroenterology·P PuolakkainenT Schröder
Sep 12, 2003·Der Internist·S WagnerP G Lankisch
May 1, 1988·Annals of Clinical Biochemistry·T A Gray, C R Paterson

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