PMID: 8594510Feb 1, 1996Paper

Iris melanomas. Diagnostic problems

Ophthalmology
D H CharS Kroll

Abstract

To illustrate some management problems with pigmented iris tumors. This is a retrospective analysis of 234 iris tumors managed by one of the authors. Five patients were selected whose clinical course and pathologic data illustrate diagnostic problems that can occur with these tumors. In the patients described, diagnostic problems were noted. In two patients, glaucoma specialists were unable to correctly diagnose an iris melanoma before filtration. One patient had a 3-clock-hour iris biopsy that was not diagnostic for malignancy, yet the enucleated eye showed melanoma. One patient with a clinically stable iris tumor had a mixed-cell melanoma. Most iris-pigmented tumors have a benign disease course. In some case, despite little clinical evidence of disease activity or progression, a melanoma, often with epithelioid cells, may be present and neither a fine-needle nor an open biopsy is always diagnostic.

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Citations

Nov 12, 2003·Survey of Ophthalmology·Flavio A Marigo, Paul T Finger
May 15, 2003·The Surgical Clinics of North America·Devron H Char
Dec 12, 2012·Pathology·Klaus G Griewank, Rajmohan Murali
Sep 1, 2001·American Journal of Ophthalmology·H DemirciS Honavar
Jul 29, 2011·American Journal of Ophthalmology·Vasileios PetousisTatyana Milman
Jan 28, 2009·Survey of Ophthalmology·Nathan M Radcliffe, Paul T Finger

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