Iron biofortification of rice using different transgenic approaches

Rice
Hiroshi MasudaNaoko K Nishizawa

Abstract

More than 2 billion people suffer from iron (Fe) deficiency, and developing crop cultivars with an increased concentration of micronutrients (biofortification) can address this problem. In this review, we describe seven transgenic approaches, and combinations thereof, that can be used to increase the concentration of Fe in rice seeds. The first approach is to enhance the Fe storage capacity of grains through expression of the Fe storage protein ferritin under the control of endosperm-specific promoters. Using this approach, the concentration of Fe in the seeds of transformants was increased by approximately 2-fold in polished seeds. The second approach is to enhance Fe translocation by overproducing the natural metal chelator nicotianamine; using this approach, the Fe concentration was increased by up to 3-fold in polished seeds. The third approach is to enhance Fe influx to the endosperm by expressing the Fe(II)-nicotianamine transporter gene OsYSL2 under the control of an endosperm-specific promoter and sucrose transporter promoter, which increased the Fe concentration by up to 4-fold in polished seeds. The fourth approach is introduction of the barley mugineic acid synthesis gene IDS3 to enhance Fe uptake and translocation w...Continue Reading

References

Mar 30, 1999·Nature Biotechnology·F GotoF Takaiwa
Feb 13, 2001·The Plant Journal : for Cell and Molecular Biology·K HiguchiS Mori
Oct 24, 2001·Plant & Cell Physiology·K IshimaruR Ohsugi
Jun 20, 2002·Journal of the American College of Nutrition·Paola LuccaIngo Potrykus
Feb 6, 2003·Planta·Rüdiger Hell, Udo W Stephan
Apr 2, 2003·Plant & Cell Physiology·Naohiro AokiRobert T Furbank
May 6, 2003·The Journal of Nutrition·Elizabeth C Theil
Mar 12, 2004·Annual Review of Plant Physiology and Plant Molecular Biology·Michael A. Grusak, Dean DellaPenna
Jul 17, 2004·The Plant Journal : for Cell and Molecular Biology·Shintaro KoikeNaoko K Nishizawa
Dec 1, 2005·The Journal of Nutrition·Jere D HaasGlenn B Gregorio
Aug 24, 2006·The Journal of Biological Chemistry·Khurram BashirNaoko K Nishizawa
Jun 15, 2007·The Plant Journal : for Cell and Molecular Biology·Yuko OgoNaoko K Nishizawa
Aug 31, 2007·Journal of Experimental Botany·Graham N ScofieldRobert T Furbank
Mar 4, 2008·Current Opinion in Plant Biology·Jorge E MayerPeter Beyer
Feb 3, 2009·Plant, Cell & Environment·Sichul Lee, Gynheung An
Apr 10, 2009·The American Journal of Clinical Nutrition·Bo Lönnerdal
Apr 21, 2009·Plant Physiology·Sichul LeeGynheung An
Jan 19, 2010·Proceedings of the National Academy of Sciences of the United States of America·Sichul LeeGynheung An
Feb 5, 2010·The Plant Journal : for Cell and Molecular Biology·Yasuhiro IshimaruNaoko K Nishizawa
Jun 29, 2010·Journal of Plant Physiology·Raul A SperottoJanette P Fett
Dec 16, 2010·The Journal of Biological Chemistry·Tomoko NozoyeNaoko K Nishizawa
Feb 25, 2011·The Journal of Nutrition·Elizabeth C Theil
May 24, 2011·The Journal of Biological Chemistry·Yasuhiro IshimaruNaoko K Nishizawa
Mar 13, 2012·Annual Review of Plant Biology·Takanori Kobayashi, Naoko K Nishizawa
May 3, 2012·Plant, Cell & Environment·Ryuichi TakahashiHiromi Nakanishi
May 31, 2012·Plant Molecular Biology·Yusuke KakeiNaoko K Nishizawa
Jun 27, 2012·The Plant Journal : for Cell and Molecular Biology·Yu ZhangJi-Ming Gong

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Citations

Nov 15, 2014·Plant Physiology and Biochemistry : PPB·Margarida P PereiraMarta W Vasconcelos
Dec 8, 2015·Journal of Agricultural and Food Chemistry·Yan HuangJinsong Bao
Sep 22, 2015·Journal of Agricultural and Food Chemistry·Taro Masuda
Aug 1, 2015·Rice·Takanori KobayashiNaoko K Nishizawa
Mar 31, 2015·Frontiers in Plant Science·Inez H Slamet-LoedinNikolaos Tsakirpaloglou
Aug 26, 2014·Trends in Plant Science·Jean-François BriatFrédéric Gaymard
Sep 28, 2016·Rice·B P Mallikarjuna SwamyInez H Slamet-Loedin
Oct 6, 2016·Critical Reviews in Biotechnology·Ellis C O'Neill, Steven Kelly
Oct 13, 2016·Journal of Experimental Botany·Soumitra PaulKarabi Datta
Nov 24, 2018·Journal of Integrative Plant Biology·Yuta Kawakami, Navreet K Bhullar
Aug 10, 2020·Physiologia Plantarum·Tirthankar Bandyopadhyay, Manoj Prasad
Oct 31, 2017·Frontiers in Plant Science·Grace Z H TanSagadevan G Mundree
Apr 25, 2020·International Journal of Molecular Sciences·Yuta Kawakami, Navreet K Bhullar
May 7, 2019·Plant & Cell Physiology·James M Connorton, Janneke Balk
Aug 15, 2020·Frontiers in Genetics·Priyanka DasArun Lahiri Majumder
Sep 26, 2020·Journal of Experimental Botany·Yuta Kawakami, Navreet K Bhullar
Jan 24, 2021·Planta·Bindu YadavOm Prakash Narayan
Jan 28, 2021·Journal of Experimental Botany·Khurram BashirNaoko K Nishizawa
May 27, 2021·Critical Reviews in Food Science and Nutrition·Deepak KasoteAhmed Regina
Jun 7, 2021·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·P Sushree ShyamliManoj Prasad
Jun 19, 2021·The New Phytologist·Sakthivel Kailasam, Edgar Peiter
Oct 25, 2021·The Science of the Total Environment·Zi YangKun-Ming Chen

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Methods Mentioned

BETA
transgenic
PCA

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