Iron-catalyzed addition of Grignard reagents to activated vinyl cyclopropanes

Chemical Communications : Chem Comm
Benjamin D Sherry, Alois Fürstner

Abstract

A highly regioselective iron-catalyzed addition of branched primary, secondary or tertiary alkyl Grignard reagents to activated vinyl cyclopropanes is described, which likely proceeds by a direct addition mechanism as opposed to single electron transfer or an iron-allyl based process.

References

Jun 26, 2001·The Journal of Organic Chemistry·D B EnglandM A Kerr
Nov 13, 2003·Angewandte Chemie·Alois Fürstner, María Méndez
Mar 31, 2004·The Journal of Organic Chemistry·Katsukiyo MiuraAkira Hosomi
Dec 9, 2004·Chemical Reviews·Carsten BolmLorenzo Zani
Jul 13, 2006·Journal of the American Chemical Society·Alois FürstnerOlivier Lepage
Jul 12, 2007·Chemical Reviews·Michael RubinVladimir Gevorgyan
Nov 2, 2007·Chemical Reviews·Alison B Flynn, William W Ogilvie
Nov 8, 2007·Journal of the American Chemical Society·Zhan LuShengming Ma
Jul 1, 2008·Accounts of Chemical Research·Benjamin D Sherry, Alois Fürstner
Jan 28, 2009·Organic Letters·Hegui GongMichel R Gagné
Apr 15, 2009·Journal of the American Chemical Society·Daisuke NodaHideo Nagashima
May 9, 2009·ChemSusChem·Waldemar Maximilian CzaplikAxel Jacobi von Wangelin
Aug 25, 2009·Angewandte Chemie·Michael HolzwarthBernd Plietker
Aug 26, 2009·Journal of the American Chemical Society·Jessica Y WuTobias Ritter

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Citations

Mar 10, 2015·Chemical Reviews·Ingmar Bauer, Hans-Joachim Knölker
Apr 24, 2015·The Journal of Organic Chemistry·JieXiang Yin, Christopher J T Hyland
Nov 28, 2012·The Journal of Organic Chemistry·Venkataraman GaneshSrinivasan Chandrasekaran
Sep 18, 2014·Organic Letters·Toolika Agrawal, Silas P Cook
Feb 25, 2017·Organic & Biomolecular Chemistry·Marta MeazzaRamon Rios
Jan 23, 2016·Organic & Biomolecular Chemistry·Ruwei CaoGaoxi Jiang
Jan 13, 2015·Chemical Communications : Chem Comm·Hong-Ying NiuHai-Ming Guo
Jul 6, 2014·Angewandte Chemie·Alois Fürstner
Sep 6, 2018·Chemistry : a European Journal·Filipe GomesAlois Fürstner
Jan 4, 2012·Angewandte Chemie·Samet Gülak, Axel Jacobi von Wangelin
Jan 22, 2013·Organic & Biomolecular Chemistry·Johannes E M N Klein, Bernd Plietker
Jul 9, 2016·Angewandte Chemie·Pierre-Georges Echeverria, Alois Fürstner
Jul 26, 2013·Chemical Communications : Chem Comm·Shuang LuoZhang-Jie Shi
Sep 12, 2020·Chemistry : a European Journal·Klaus BanertA Daniel Boese
Jan 7, 2010·Organic Letters·Pascal CératAndré B Charette
Apr 10, 2018·The Journal of Organic Chemistry·Klaus BanertTharallah Shoker
May 7, 2013·Journal of the American Chemical Society·Roger R Nani, Sarah E Reisman
Nov 14, 2017·The Journal of Organic Chemistry·Yi Sing GeeChristopher J T Hyland
Sep 14, 2021·The Journal of Organic Chemistry·Fang-Fang FengDominique Cahard

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