Iron-Folic Acid Supplementation During Pregnancy Reduces the Risk of Stunting in Children Less Than 2 Years of Age: A Retrospective Cohort Study from Nepal

Nutrients
Yasir Bin NisarVictor M Aguayo

Abstract

The aim of the study was to investigate the effect of antenatal iron-folic acid (IFA) supplementation on child stunting in Nepalese children age <2 years. A retrospective cohort study design was used, in which a pooled cohort of 5235 most recent live births 2 years prior to interview from three Nepal Demographic and Health Surveys (2001, 2006 and 2011) was analysed. The primary outcome was stunting in children age <2 years. The main exposure variable was antenatal IFA supplementation. Multivariate Poisson regression analysis was performed. In our sample, 31% and 10% of Nepalese children age <2 years were stunted and severely stunted, respectively. The adjusted relative risk of being stunted was 14% lower in children whose mothers used IFA supplements compared to those whose mothers did not use (aRR = 0.86, 95% CI = 0.77-0.97). Additionally, the adjusted relative risk of being stunted was significantly reduced by 23% when antenatal IFA supplementation was started ≤6 months with ≥90 IFA supplements used during pregnancy (aRR = 0.77, 95% CI = 0.64-0.92). Antenatal IFA supplementation significantly reduced the risk of stunting in Nepalese children age <2 years. The greatest impact on the risk reduction of child stunting was when IF...Continue Reading

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Citations

Jun 28, 2019·Statistics in Medicine·Oleg SysoevKatarina Ekholm Selling
Jul 20, 2019·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Junxiang WeiYoufa Wang
Mar 25, 2019·Maternal & Child Nutrition·Juan Miguel Martínez-GalianoMiguel Delgado-Rodriguez
Aug 30, 2020·The American Journal of Clinical Nutrition·Tyler VaivadaZulfiqar A Bhutta
Sep 6, 2020·The American Journal of Clinical Nutrition·Kaitlin ConwayZulfiqar A Bhutta
Sep 25, 2021·Biomédica : revista del Instituto Nacional de Salud·Paola Rueda-GuevaraAndrea Ramírez

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