PMID: 3851675Nov 1, 1985

Iron stores in female blood donors evaluated by serum ferritin

Blut
Nils MilmanC M Sørensen

Abstract

Iron stores were evaluated by serum ferritin determinations in 948 menstruating and 141 non-menstruating female blood donors. Blood donation was associated with a decrease in ferritin. First-time donors (n = 163) had a geometric mean ferritin of 24 micrograms/l and multiple-time donors a value of 19 micrograms/l (p less than 0.01). In the donating population 31.5% had ferritin values less than 15 micrograms/l (i.e. depleted iron stores). Menstruating donors had lower mean serum ferritin than non-menstruating donors (p less than 0.001), and a higher frequency of ferritin values less than 15 micrograms/l (p less than 0.05). There was no relationship between ferritin levels and the number of pregnancies. The frequency of donations was more predictive of ferritin levels than the number of donations. Mean ferritin displayed a moderate fall up to the 2nd donation, and was hereafter relatively constant, whereas an increase in donation frequency was accompanied by a significant decrease in ferritin. Female donors, especially when phlebotomised greater than or equal to 3 times per year, should have their iron status checked at appropriate intervals by measurement of serum ferritin and should be advised regular iron supplementation.

References

Dec 1, 1977·Clinical Science and Molecular Medicine·R CharltonT Bothwell
Jan 1, 1978·Scandinavian Journal of Haematology·N S Pedersen, N Morling
Feb 1, 1973·Klinische Wochenschrift·H C HeinrichH Busch
Oct 1, 1973·Journal of Clinical Pathology·G O WaltersM Worwood
Sep 1, 1968·The American Journal of Medicine·R GreenM Layrisse
Jan 1, 1982·Progress in Neurobiology·R C Frederickson, L E Geary
Nov 1, 1984·Transfusion·Nils Milman, M Søndergaard
Nov 1, 1984·Transfusion·T L SimonP J Garry
Dec 7, 1964·JAMA : the Journal of the American Medical Association·J A PRITCHARD, R A MASON

Citations

Jan 1, 1992·Annals of Hematology·Nils Milman, Marianne Kirchhoff
Jun 29, 2011·Annals of Hematology·Nils Milman
Oct 13, 2009·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·A S RøsvikT Hervig
Nov 28, 2001·Hematology·G M BrittenhamR S Ajioka
Jun 14, 2020·Transfusion·Marieke VinkenoogMart P Janssen
Nov 11, 2005·The American Journal of Clinical Nutrition·Heidi Michels BlanckMichele Reyes

Related Concepts

Blood Donor
Bloodletting
Isoferritin
Eryhem
Iron
Menstruation

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