Irradiated macula flava in the human vocal fold mucosa

American Journal of Otolaryngology
Kiminori SatoTadashi Nakashima

Abstract

There have been no investigations regarding radiation-induced damage on human maculae flavae (MFs) in the vocal fold mucosa (VFM) and on stellate cells (SC) in the MF. The VFM, especially MF, after irradiation was investigated histologically. The lamina propria of the irradiated VFM was investigated in 5 human adult vocal folds by light and electron microscopy. Fibroblasts in the irradiated Reinke's space (RS) showed no morphological changes. Irradiated RS was composed of fibrous tissue with increased collagenous fibers. Most of the SC in the irradiated MF had dark cytoplasm. The nucleus-cytoplasm ratio was relatively small, but there were few intracellular organelles in the cytoplasm. Some SC showed degeneration. Fewer vesicles were present at the periphery of the cytoplasm. The MF was rather deficient in fibrous components. Elastic and collagenous fibers immediately surrounding SC in the irradiated MF were lower in number than usual, but elastic fibers and collagenous fibers composed of irregular collagen fibrils could be detected at a distance from SC. It was suggested that precursors of collagenous and elastic fibers synthesized by SC were damaged by irradiation. Radiation sensitivity of SC was higher than that of conventio...Continue Reading

References

Jan 1, 1968·Archives of Biochemistry and Biophysics·L De Luca, G Wolf
Jan 11, 1966·Biochimica Et Biophysica Acta·P R Sundaresan
Jul 1, 1995·The Annals of Otology, Rhinology, and Laryngology·K Sato, M Hirano
Feb 1, 1995·The Annals of Otology, Rhinology, and Laryngology·K Sato, M Hirano
Nov 1, 1995·The Annals of Otology, Rhinology, and Laryngology·K Sato, M Hirano
Jan 1, 1997·The Annals of Otology, Rhinology, and Laryngology·K Sato, M Hirano
Dec 29, 1998·The Annals of Otology, Rhinology, and Laryngology·K Sato
Jun 16, 1999·The Laryngoscope·S D GrayT H Hammond
Feb 24, 2000·The Annals of Otology, Rhinology, and Laryngology·K SatoT Nakashima
Apr 20, 2001·The Annals of Otology, Rhinology, and Laryngology·K SatoT Nakashima
May 25, 2001·The Annals of Otology, Rhinology, and Laryngology·K SatoT Nakashima
Jan 22, 2002·The Annals of Otology, Rhinology, and Laryngology·Kiminori SatoTadashi Nakashima
Mar 11, 2003·Acta Oto-laryngologica·Kiminori SatoTadashi Nakashima
Apr 19, 2003·Acta Oto-laryngologica·Kiminori SatoTadashi Nakashima
Sep 2, 2005·The Annals of Otology, Rhinology, and Laryngology·Kiminori Sato, Tadashi Nakashima
Nov 2, 2006·The Annals of Otology, Rhinology, and Laryngology·Kiminori SatoTadashi Nakashima

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Citations

Nov 8, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·D M HartlJ C Soria
Jan 14, 2011·Journal of Voice : Official Journal of the Voice Foundation·Kiminori SatoYasuaki Harabuchi
Apr 22, 2015·The Laryngoscope·Songyi LeeJae-Yol Lim
Dec 17, 2009·The Annals of Otology, Rhinology, and Laryngology·Kiminori SatoYasuaki Harabuchi
Jan 25, 2013·The Annals of Otology, Rhinology, and Laryngology·Kiminori SatoTadashi Nakashima
Jan 2, 2009·The Laryngoscope·Kiminori Sato, Tadashi Nakashima
Jan 1, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·D M HartlJ C Soria

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