Irregularities on the surface of single-piece AcrySof SA60AT intraocular lenses

Journal of Cataract and Refractive Surgery
Dan Q NguyenAdrian K Bates

Abstract

To report a case series of what initially appeared to be macroscopic biomaterial deposits and irregularities on the surface of AcrySof SA60AT intraocular lenses (IOLs) (Alcon Inc.) Department of Ophthalmology and Somerset Hospital, Taunton, United Kingdom; Department of Ophthalmology and Visual Sciences, John A Moran Eye Center, University of Utah, Salt Lake City, Utah, USA; and Intraocular Implant Unit, Sydney Eye Hospital, University of Sydney, Sydney, Australia. Twelve AcrySof SA60AT IOLs were initially thought to have irregularities on their surfaces when examined under the operating microscope before implantation in the capsular bag during cataract surgery. The IOLs were sent for further analysis, including gross examination and light and scanning electron microscopy, to John A. Moran Eye Center, Salt Lake City, Utah, USA, and to Alcon Laboratories, Hemel Hempstead, United Kingdom. Light microscopy revealed the presence of irregular fine lesions on the IOLs' optics and haptics. The lesions consisted of elevations and depressions of the IOL surface that were present on both the anterior and the posterior surfaces of the IOLs. Scanning electron microscopy confirmed the presence of physical/mechanical damage to the IOLs, whic...Continue Reading

References

Apr 1, 1978·Ophthalmology·R C DrewsN Okun
Jan 1, 1989·Journal of Cataract and Refractive Surgery·K OharaT Akahoshi
Jan 1, 1985·Ophthalmology·J R Wolter
Feb 15, 1985·American Journal of Ophthalmology·M C KincaidE R Rashid
Jan 1, 1984·Journal - American Intra-Ocular Implant Society·N MamalisR J Olson
Jul 1, 1984·Survey of Ophthalmology·D J AppleR J Olson
Jan 1, 1996·Journal of Cataract and Refractive Surgery·T KohnenD D Koch
Mar 22, 2003·Journal of Cataract and Refractive Surgery·Naoyuki YamakawaMasahiko Usui
Mar 20, 2004·Journal of Cataract and Refractive Surgery·Rita MencucciUgo Menchini

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Citations

Apr 2, 2013·American Journal of Ophthalmology·Hon Shing OngMark R Wilkins
May 30, 2016·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Dhivya Ashok KumarJosheela Sheebakalyani Gnanaprakasam

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