IRRITABLE BOWEL SYNDROME, FOOD INTOLERANCE AND NON- CELIAC GLUTEN SENSITIVITY. A NEW CLINICAL CHALLENGE

Arquivos De Gastroenterologia
Rosa Leonôra Salerno Soares

Abstract

Approximately 80% of irritable bowel syndrome (IBS) patients report that their symptoms are triggered after ingesting one or specific food groups. Gluten, wheat and related proteins (e.g., amylase-trypsin inhibitors, and fermentable oligo-di-mono-saccharides and polyols (FODMAPs) are the most relevant IBS symptom triggers, although the true 'culprit(s)' is/are still not well established. The concept of causal relationship between gluten intake and the occurrence of symptoms in the absence of celiac disease and wheat allergy was termed non-celiac gluten sensitivity (NCGS). The borderline between celiac disease, wheat allergy, IBS and NCGS is not always clearly distinguishable, and the frequency and clinical identity of NGCS are still unclear. An overlap between IBS and NCGS has been detected. The incomplete knowledge of the etiopathogenesis of these clinical conditions, lack of data on their real epidemiology, as well as the absence of a gold standard for their diagnosis, make the overall picture difficult to understand "It is crucial to well define the interaction between IBS, food intolerance and NGCS, since the role of diet in IBS and its dietary management is an essential tool in the treatment of a large number of these pati...Continue Reading

References

Jun 24, 1978·Lancet·A Ellis, B D Linaker
Sep 1, 1992·Gastroenterology·S E Crowe, M H Perdue
Nov 9, 1985·Lancet·M A SmithR Finn
Dec 14, 1985·Lancet·S P Calloway, P Fonagy
May 7, 1994·Lancet·E YoungR Rona
Mar 13, 2001·Digestion·M SimrénE S Björnsson
Dec 26, 2001·Digestive Diseases·E A MayerL Chang
May 23, 2002·Annals of the New York Academy of Sciences·P E R Brandtzaeg
Mar 26, 2003·The American Journal of Gastroenterology·George F LongstrethJoshua J Ofman
Apr 27, 2004·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·R L S SoaresJ M Santos
Sep 24, 2004·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Piero VerniaRenzo Caprilli
Jul 29, 2005·Digestive Diseases and Sciences·Ragna LindArnold Berstad
Aug 20, 2005·Scandinavian Journal of Gastroenterology·Sameer ZarDevinder Kumar
Dec 13, 2005·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·R L S SoaresV R S R Rocha
Jan 5, 2006·European Journal of Clinical Nutrition·K W MonsbakkenP G Farup
May 9, 2006·Gastroenterology·Douglas A Drossman
May 9, 2006·Gastroenterology·George F LongstrethRobin C Spiller
May 12, 2006·World Journal of Gastroenterology : WJG·Dae-Won JunSang-Hoen Cho
Mar 27, 2007·Gastroenterology·Tobias LiebregtsGerald Holtmann
Jun 8, 2007·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Ulrich WahnschaffeReiner Ullrich
May 22, 2008·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·N HusainF Creed
Jun 25, 2010·Acta Paediatrica·Massimiliano DonMatti Korppi
Nov 26, 2010·Current Opinion in Gastroenterology·Joseph Y Chang, Nicholas J Talley
Feb 22, 2011·Gastroenterology Clinics of North America·Shanti EswaranWilliam D Chey
May 24, 2011·Journal of Neurogastroenterology and Motility·Yukari TanakaDouglas A Drossman
Jul 14, 2011·Nature Reviews. Neuroscience·Emeran A Mayer
Mar 20, 2012·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Rebecca M Lovell, Alexander C Ford
Apr 11, 2012·The American Journal of Gastroenterology·Peter R Gibson, Susan J Shepherd
Jul 28, 2012·American Journal of Physiology. Gastrointestinal and Liver Physiology·Michael CamilleriWen Zhou
Dec 5, 2012·The Journal of Experimental Medicine·Yvonne JunkerDetlef Schuppan
Oct 1, 2013·Nutrients·Carlo CatassiAlessio Fasano
Nov 13, 2013·European Journal of Gastroenterology & Hepatology·Imran AzizDavid S Sanders
Apr 18, 2014·Public Health Nutrition·Sinéad GolleyPhilip Mohr
Apr 18, 2014·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Jessica R BiesiekierskiPeter R Gibson
Jun 3, 2014·BMC Medicine·Umberto VoltaUNKNOWN Study Group for Non-Celiac Gluten Sensitivity
Aug 5, 2014·European Journal of Gastroenterology & Hepatology·Raffaella DaineseThierry Piche
Sep 19, 2014·World Journal of Gastroenterology : WJG·Rosa L S Soares

❮ Previous
Next ❯

Citations

May 27, 2020·Current Opinion in Clinical Nutrition and Metabolic Care·Dorota Mańkowska-Wierzbicka, Marta Stelmach-Mardas
Jun 3, 2021·Medicina·Feliznando Isidro Cárdenas-TorresNoé Ontiveros

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.