Is a quantitative risk assessment of air quality in underground parking garages possible?

Indoor Air
P GlorennecR Alary

Abstract

Little information is available about the health risks associated with time spent in underground parking garages. The objective of this study was to determine whether it is possible to quantify the health risks associated with these garages without epidemiologic data on the subject. We followed the standard procedure for health risk assessment. We searched the literature for pollutant concentrations in the air samples of underground parking garages, the hazards associated with their inhalation, and their toxicological reference values. Conditions of occupational and user exposure were estimated by scenarios and taken into account to discuss toxicological reference values by modifying (with Haber's law) the adjustment factors for exposure frequency and duration. Risk quantification was possible for 39 pollutants. Acute exposures to CO and NO2 exceed toxicological reference values, as does chronic exposure to benzene for threshold effects. The risk of a carcinogenic effect associated with benzene may be greater than 10(-5). Excess exposure to air pollution indicators (PM and NO2) is also elevated, judging by the WHO Air Quality Guidelines, and also when comparing to levels with reported effects in epidemiologic studies. The risk ...Continue Reading

References

Jun 1, 1985·Regulatory Toxicology and Pharmacology : RTP·E J Calabrese
Jun 10, 1998·Regulatory Toxicology and Pharmacology : RTP·A G Renwick, N R Lazarus
Sep 9, 1999·Toxicological Sciences : an Official Journal of the Society of Toxicology·H Witschi
May 31, 2001·Environmental Toxicology and Pharmacology·S DekkersM A.J. Rennen
Mar 7, 2002·JAMA : the Journal of the American Medical Association·C Arden PopeGeorge D Thurston
Mar 15, 2002·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·S M BarlowP Steinberg
Oct 29, 2002·Lancet·Bert Brunekreef, Stephen T Holgate
Feb 1, 2003·Toxicology Letters·Melvin E Andersen
Jan 23, 2004·Toxicological Sciences : an Official Journal of the Society of Toxicology·Samuel M CohenDorothy Patton
Sep 15, 2004·Journal of Epidemiology and Community Health·S MedinaUNKNOWN Apheis group
Mar 17, 2006·The European Respiratory Journal·E SamoliK Katsouyanni
Apr 11, 2006·Inhalation Toxicology·Dennis ShustermanAndrew Salmon
Aug 22, 2006·Journal of Hazardous Materials·Maureen F Orr, Perri Zeitz Ruckart
Jun 26, 2007·Environmental Health Perspectives·Felicia WuMeryl H Karol
Jun 26, 2007·Environmental Health Perspectives·Clifford S MitchellMeryl H Karol
Jun 26, 2007·Environmental Health Perspectives·Olaf C G AdanFelicia Wu

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Citations

Dec 2, 2017·Environmental Science and Pollution Research International·Mariusz MarćBożena Zabiegała
Aug 22, 2021·Environmental Science and Pollution Research International·Seyed Milad AtaeiFarhad Hadadi

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