Is a targeted intensive intervention effective for improvements in hypertension control? A randomized controlled trial

Family Practice
L ReutherJens Søndergaard

Abstract

High blood pressure (BP) is one of the most important risk factors for stroke, and antihypertensive therapy significantly reduces the risk of cardiovascular morbidity and mortality. However, achieving a regulated BP in hypertensive patients is still a challenge. To evaluate the impact of an intervention targeting GPs' management of hypertension. A cluster randomized trial comprising 124 practices and 2646 patients with hypertension. In the Capital Region of Denmark, the participating GPs were randomized to an intensive or to a moderately intensive intervention group or to a control group and in Region Zealand and Region of Southern Denmark, practices were randomized into a moderately intensive intervention and to a control group. The main outcome measures were change in proportion of patients with high BP and change in systolic BP (SBP) and diastolic BP (DBP) from the first to the second registration. The proportion of patients with high BP in 2007 was reduced in 2009 by ~9% points. The mean SBP was reduced significantly from 2007 to 2009 by 3.61 mmHg [95% confidence interval (CI): -4.26 to -2.96], and the DBP was reduced significantly by 1.99 mmHg (95% CI: -2.37 to -1.61). There was no additional impact in either of the interv...Continue Reading

Associated Clinical Trials

Aug 16, 2019·Anders Elkær Jensen

References

Aug 16, 1997·BMJ : British Medical Journal·R Grol
Jul 25, 2003·Scandinavian Journal of Primary Health Care·Claudia M LoboJohannes C van der Wouden
Feb 1, 2008·The Journal of Clinical Hypertension·William J Elliott
Apr 1, 2008·Journal of General Internal Medicine·Leroi S HicksDavid W Bates
Nov 26, 2009·Scandinavian Journal of Primary Health Care·Jarja IjäsMarjukka Mäkelä
Jan 1, 2009·Journal of the American Society of Hypertension : JASH·Christel N KronborgIb A Jacobsen
Mar 23, 2011·Journal of the American Medical Informatics Association : JAMIA·Monique W M JaspersLinda W Peute
May 21, 2011·Family Practice·M S PaulsenM Andersen

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