Is acetabular dysplasia and pelvic deformity properly interpreted in patients with congenital femoral deficiency? A 3D analysis of pelvic computed tomography

Journal of Children's Orthopaedics
Bartosz MusielakMarek Jóźwiak

Abstract

The aim of this study is to assess the pelvis's morphology and spatial orientation of the acetabulum, and their relation to the severity of Congenital Femoral Deficiency (CFD) using 3D imaging. Defining these pathologies is crucial for adequate surgical correction. The shape and structure of the acetabulum and pelvis were evaluated in 14 children with unilateral CFD via 3D computed tomography (CT) scans, and then analysed with geometric morphometrics (Procrustes ANOVA). The association between pelvic directional asymmetry and CFD classifications (Aitken, Paley) was assessed. The affected acetabulum's orientation was compared to the non-affected side, and the variability of orientation in different CFD types was evaluated (bivariate correlation). The hemipelvis with CFD is characterized by a smaller acetabulum, a laterally curved ischium and a less upright ilium (p < 0.001). Multivariate regressions revealed a greater level of pelvis asymmetry in more severe types of CFD (p < 0.001). The acetabulum orientation assessment showed a significant decrease in mean anteversion (1.3°) and inclination (9.6°) angle, when compared to the non-affected side (26°and 17.1° respectively; p < 0.001). The affected side of the pelvis is considerab...Continue Reading

References

Jan 1, 1992·International Orthopaedics·J Albiñana-CilvetiC Miralles-Flores
Feb 5, 2003·Clinical Orthopaedics and Related Research·K A SiebenrockR Ganz
Sep 13, 2011·Pediatric Radiology·David M BikoDiego Jaramillo
Oct 1, 2011·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Allston J StubbsJoel D Stitzel
Dec 20, 2014·Clinical Orthopaedics and Related Research·Harold van BossePaul Babyn
May 31, 2016·American Journal of Human Biology : the Official Journal of the Human Biology Council·Anna Maria KubickaJanusz Piontek
Sep 30, 2016·International Orthopaedics·Mark EidelmanJohn E Herzenberg
Nov 11, 2016·Clinical Orthopaedics and Related Research·Jeffrey J NeppleJohn C Clohisy
Oct 10, 2018·Journal of Pediatric Orthopedics·Jason P CaffreyVidyadhar V Upasani

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Citations

Jun 23, 2021·The Journal of Bone and Joint Surgery. American Volume·Andrew G GeorgiadisMark T Dahl

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Software Mentioned

R
GraphPadInstat
Landmark
InVesalius
R Foundation for Statistical
ScanIP
Procrustes
MorphoJ
IDAV

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