Is Cardiorespiratory Fitness Related to Cardiometabolic Health and All-Cause Mortality Risk in Patients with Coronary Heart Disease? A CARE CR Study

Sports Medicine - Open
Simon NicholsLee Ingle

Abstract

Higher cardiorespiratory fitness (CRF) is associated with lower morbidity and mortality in patients with coronary heart disease (CHD). The mechanisms for this are not fully understood. A more favourable cardiometabolic risk factor profile may be responsible; however, few studies have comprehensively evaluated cardiometabolic risk factors in relation to CRF amongst patients with CHD. We aimed to explore differences in cardiometabolic risk and 5-year all-cause mortality risk in patients with CHD who have low, moderate, and high levels of CRF. Patients with CHD underwent maximal cardiopulmonary exercise testing, echocardiogram, carotid intima-media thickness measurement, spirometry, and dual X-ray absorptiometry assessment. Full blood count, biochemical lipid profiles, high-sensitivity (hs) C-reactive protein, and NT-proBNP were analysed. Patients were defined as having low, moderate, or high CRF based on established prognostic thresholds. Seventy patients with CHD (age 63.1 ± 10.0 years, 86% male) were recruited. Patients with low CRF had a lower ventilatory anaerobic threshold, peak oxygen pulse, post-exercise heart rate recovery, and poor ventilatory efficiency. The low CRF group also had higher NT pro-BNP, hs-CRP, non-fasting ...Continue Reading

References

Sep 1, 1989·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·N B SchillerI Schnittger
Jun 1, 1986·Journal of Applied Physiology·W L BeaverB J Whipp
Nov 1, 1996·Journal of the American College of Cardiology·A L ClarkA J Coats
Mar 15, 2002·The New England Journal of Medicine·Jonathan MyersJ Edwin Atwood
Jan 14, 2003·American Journal of Respiratory and Critical Care Medicine·UNKNOWN American Thoracic Society, UNKNOWN American College of Chest Physicians
Dec 19, 2003·Journal of the American College of Cardiology·Terence KavanaghRoy J Shephard
Feb 5, 2004·American Heart Journal·Ross ArenaMary Ann Peberdy
Dec 5, 2006·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Nico R Van de VeireJohan De Sutter
Jul 17, 2007·Journal of the American College of Cardiology·Torbjørn OmlandUNKNOWN PEACE Investigators
Jul 29, 2008·American Heart Journal·Steven J KeteyianPhilip A Ades
Nov 27, 2009·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Sandra MandicVictor F Froelicher
Jun 30, 2010·Circulation·Gary J BaladyUNKNOWN Interdisciplinary Council on Quality of Care and Outcomes Research
Nov 22, 2011·American Journal of Physiology. Heart and Circulatory Physiology·David C PooleTimothy I Musch
Apr 17, 2012·Mayo Clinic Proceedings·Paul A McAuleySteven N Blair
May 4, 2013·Mayo Clinic Proceedings·Billie-Jean MartinUNKNOWN APPROACH Investigators
Jan 1, 2014·European Heart Journal Cardiovascular Imaging·Davide VanoliUlf Näslund
Feb 18, 2014·Journal of the American College of Cardiology·Carl J LavieSteven N Blair
Jan 31, 2015·European Journal of Preventive Cardiology·Ellen CoeckelberghsLuc Vanhees
Apr 9, 2015·British Journal of Hospital Medicine·Claire TaylorLee Ingle
May 12, 2015·British Journal of Hospital Medicine·Simon NicholsLee Ingle

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Citations

Aug 17, 2020·Journal of Cardiopulmonary Rehabilitation and Prevention·Jason L RengoPhilip A Ades
Aug 20, 2020·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Kenneth Shinkichi NoguchiAda Tang
Mar 30, 2021·Frontiers in Physiology·Marc JörresMathias Steinach
Jul 29, 2021·Cardiovascular Diabetology·Francisco J Osuna-PrietoSonia Fernández-Veledo

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Methods Mentioned

BETA
coronary artery bypass
X-ray
blood draw

Software Mentioned

Lunar iDXA
CALIBER

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