Is cell salvage safe in liver resection? A pilot study

Journal of Clinical Anesthesia
Annette SchmidtHendrik W Gervais

Abstract

To investigate the quality of cell salvaged (CS) blood in patients undergoing hemihepatectomy (study group) and compare it with CS-blood from aortic surgery (control group). Observational study. Operating room in a university hospital. 6 patients undergoing hemihepatectomy or aortobifemoral bypass with intraoperative blood loss of more than 800 mL. Samples were drawn from the central venous catheter, from the reservoir of a CS recovery system, and from the processed blood in each patient to determine interleukin (IL)-6, IL-8, IL-10, tumor necrosis factor (TNF), complement C3a, and the terminal complement complex C5b-9. Microbiological analysis included colony count after cultivation in aerobic and anaerobic medium as well as enrichment culture for 6 days. In the hemihepatectomy group, levels of IL-6, C3a, and C5b-9 were significantly higher in the reservoir than in samples obtained from the central venous catheter. After the washing procedure, levels of IL-6, C3a, and C5b-9 were lower in the liver resection group than in each patient's own plasma levels. In all patients undergoing aortobifemoral bypass and in 5 patients undergoing hemihepatectomy, blood samples were sterile or showed growth of commensal skin microflora in low n...Continue Reading

References

Jan 1, 1991·Anesthesia and Analgesia·Y KangL K Martin
Sep 1, 1990·Anesthesiology·J P BengtsonA Bengtsson
Apr 18, 2001·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·I AnderssonA Bengtsson
Jan 17, 2002·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Y SugaiA Fuse
Sep 28, 2002·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Emil HansenJuergen Altmeppen
Oct 29, 2002·Anesthesia and Analgesia·Jonathan H WatersMatthew T Karafa
Sep 10, 2003·Anesthesiology·Jonathan H WatersGary Procop
Dec 9, 2004·Transfusion·Ernil Hansen, Michael Pawlik Hansen
Dec 13, 2005·Critical Care Medicine·Philip O Scumpia, Lyle L Moldawer
May 31, 2006·The Journal of Thoracic and Cardiovascular Surgery·Martin WesterbergAnders Jeppsson
Jun 8, 2006·Transplantation Proceedings·O CuomoG Marino Marsilia

❮ Previous
Next ❯

Citations

May 8, 2016·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Madeline LemkePaul J Karanicolas

❮ Previous
Next ❯

Related Concepts

Related Feeds

Alternative Complement Pathway

The Alternative Complement Pathway is part of the innate immune system, and activation generates membrane attack complexes that kill pathogenic cells. Discover the latest research on the Alternative Complement Pathway.