Is Coincidental Rhinosinusitis a Predisposing Factor for Postoperative Central Nervous System Infection After Endoscopic Endonasal Transsphenoidal Surgery?

The Journal of Craniofacial Surgery
Do Hyun KimSung Won Kim

Abstract

To investigate the effect of rhinosinusitis in patients who undergo surgery via the endoscopic endonasal transsphenoidal approach (EETSA). The authors retrospectively reviewed the medical records of patients who underwent surgery via the EETSA between February 2009 and November 2016. In total, 505 patients were included in the study. Preoperative paranasal sinus computed tomography, sellar magnetic resonance imaging, and nasal endoscopy were performed for all the patients. Fifteen patients without sphenoid sinusitis underwent surgery with the concomitant transsphenoidal approach and functional endoscopic sinus surgery, and showed no central nervous system (CNS) complication. During surgery via the EETSA, the presence of rhinosinusitis did not significantly affect the incidence of postoperative CNS infection (P = 0.051), except for sphenoid sinusitis (P = 0.003). Conversely, the incidence of postoperative CNS infection was not related significantly to the Lund-Mackay score or tumor size. The risk of CNS infection was 12.151-fold higher in patients with sphenoid sinusitis (95% confidence interval, 3.153-46.827; P ≤ 0.001). Surgery via the EETSA and functional endoscopic sinus surgery can be safely performed together in most patie...Continue Reading

References

Nov 14, 1997·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M O van AkenW W de Herder
Jul 1, 2005·Neurosurgery·A Samy YoussefHarry R van Loveren
Jun 8, 2006·Otolaryngologic Clinics of North America·Dharambir S Sethi, Jern-Lin Leong
Sep 29, 2006·Expert Review of Anticancer Therapy·Wael MuslehMaciej S Lesniak
Sep 22, 2007·American Journal of Rhinology·Brent UrenPeter-John Wormald
Aug 2, 2008·Journal of Neurosurgery·Andreas StadlbauerOliver Ganslandt
Oct 29, 2008·American Journal of Rhinology·Kyung Wook Heo, Seong Kook Park
Jun 26, 2010·The Laryngoscope·Brian RotenbergNeil Duggal
Jan 18, 2014·Journal of Neurological Surgery. Part B, Skull Base·Madeleine R SchabergMarc R Rosen
Sep 28, 2014·Pituitary·Henry Ka-Fung MakMax Wintermark
Feb 14, 2015·International Forum of Allergy & Rhinology·Gurston G NyquistMarc R Rosen
May 8, 2016·Cephalalgia : an International Journal of Headache·Bin YuFang Luo
May 24, 2016·The Journal of Craniofacial Surgery·Gonul GuvencNurullah Yuceer

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.