Is core needle biopsy superior to fine-needle aspiration biopsy in the diagnosis of papillary breast lesions?

Diagnostic Cytopathology
Shahla MasoodWalid E Khalbuss

Abstract

Since the 1980s core needle biopsy (CNB) has gained remarkable popularity and in many institutions it has replaced fine-needle aspiration biopsy (FNAB). However, similar to FNAB, limitation remains in the ability of this procedure to reliably diagnose a small, but prognostically significant, number of breast lesions. These include entities such as atypical ductal hyperplasia, fibro-epithelial tumors, radial scar, papillary lesions, and lobular neoplasia. To assess the diagnostic accuracy of CNB vs. FNAB in the same breast lesions, we reviewed our cases of papillary lesions of the breast. In a retrospective study, we identified 36 cases of FNAB and 11 cases of CNB diagnosed as papillary lesions and compared the results with their corresponding surgical specimen. Interpretation ranged from papillary vs. atypical papillary lesions favoring benign vs. malignant tumors, respectively. Occasionally, definitive diagnosis of papillary carcinoma was entertained. Immunohistochemical staining with smooth muscle actin was used to evaluate the presence or absence of a myoepithelial cell layer. FNAB had benign findings in 21 lesions, atypical in 10, and malignant in five. Of the five lesions yielding malignant features, four had invasive carc...Continue Reading

References

Jul 1, 1977·Human Pathology·T M MuradP Pritchett
Jan 1, 1992·Diagnostic Cytopathology·A P Dei TosL Bittesini
Sep 1, 1990·Radiology·S H ParkerB J Burke
Jan 1, 1994·Diagnostic Cytopathology·R H BardalesM W Stanley
Apr 1, 1994·AJR. American Journal of Roentgenology·J J GisvoldS H Jung
Jan 21, 1993·International Journal of Cancer. Journal International Du Cancer·V I GuelsteinA V Ljubimov
Feb 1, 1996·Radiology·D D DershawA F Abramson
Feb 4, 1999·AJR. American Journal of Roentgenology·L LibermanP P Rosen
Jan 3, 2001·Cancer·L LibermanD D Dershaw
Jun 8, 2001·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·H M VerkooijenUNKNOWN COBRA Study Group
May 1, 1962·Cancer·F T KRAUS, R D NEUBECKER

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Citations

Jun 8, 2010·Breast Cancer Research and Treatment·Gary M Tse, Puay-Hoon Tan
Oct 21, 2004·Journal of the National Cancer Institute·Carol J FabianMatthew S Mayo
Feb 14, 2006·Annals of Surgical Oncology·Edna K ValdesAlison Estabrook
Jan 9, 2007·Annals of Surgical Oncology·Edna K ValdesSusan K Boolbol
Jun 6, 2007·Annals of Surgical Oncology·Vance SohnTommy Brown
Apr 25, 2006·AJR. American Journal of Roentgenology·W W M LamT K F Ma
Apr 25, 2006·AJR. American Journal of Roentgenology·Laura LibermanD David Dershaw
Apr 29, 2008·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·R SakrS Uzan
Nov 26, 2005·Clinics in Laboratory Medicine·Andrea Abati, Aylin Simsir
Nov 21, 2008·Diagnostic Cytopathology·Aylin SimsirJoan Cangiarella
May 25, 2006·Cancer·Michelle D Reid-NicholsonAndre L Moreira
Oct 12, 2004·American Journal of Surgery·Leah S GendlerSusan K Boolbol
Mar 1, 2005·International Journal of Surgical Pathology·Gianni Simone
Jun 27, 2007·Clinical Breast Cancer·Warren M RozenCraig Murphy
Nov 11, 2018·ANZ Journal of Surgery·Yue YuPhilip J Crowe
May 2, 2007·Advances in Anatomic Pathology·Anna Marie Mulligan, Frances P O'Malley
Jan 17, 2012·Diagnostic Cytopathology·Marilin Rosa, Shahla Masood
Feb 10, 2021·Cancer Cytopathology·Shirley Kristina JamidiGary M Tse
Dec 21, 2004·Cytopathology : Official Journal of the British Society for Clinical Cytology·T Levine
Nov 8, 2020·Human Pathology·Lawrence Hsu LinFarbod Darvishian
Jun 6, 2009·Archives of Pathology & Laboratory Medicine·Shir-Hwa UengFattaneh A Tavassoli

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