PMID: 8943121Nov 1, 1996Paper

Is delayed surgery really better for congenital diaphragmatic hernia?: a prospective randomized clinical trial

Journal of Pediatric Surgery
M N de la HuntJ Wagget

Abstract

Delayed surgery has become widely accepted in the management of congenital diaphragmatic hernia after comparing outcomes only with historical retrospective controls. It was the aim of this study to compare early and delayed hernia repair in a randomized prospective clinical trial. Fifty-four infants were randomized to receive either early repair (within 4 hours of admission) or delayed repair (more than 24 hours after birth). The survival rate was higher for the delayed group (57% v 46%), but the difference was not significant (difference: -11; 95% confidence limits: -37.5, 15.5). There were no significant differences between the two groups with respect to length of hospital stay, ventilator dependency, or survival time. Recorded preoperative risk factors were similar for the two groups. Eight infants in the delayed repair group died without having undergone surgery. The optimum time for surgery still needs clarification.

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Citations

Oct 24, 2012·Pediatric Surgery International·Massimo GarriboliAgostino Pierro
Jun 10, 2010·Indian Journal of Pediatrics·V JainV Bhatnagar
Apr 18, 2008·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Kathleen S Hartnett
Jun 26, 2014·Surgery·Laura E HollingerUNKNOWN Congenital Diaphragmatic Hernia Study Group
Dec 3, 2014·Seminars in Fetal & Neonatal Medicine·Enrico Danzer, Holly L Hedrick
Jul 30, 2002·Seminars in Pediatric Surgery·Ronald B Hirschl
Jan 30, 2002·Seminars in Pediatric Surgery·Martin L Blakely, Kevin P Lally
Apr 28, 2007·Seminars in Pediatric Surgery·Matthew T Harting, Kevin P Lally
Jan 31, 2013·Pediatrics International : Official Journal of the Japan Pediatric Society·Masahiro HayakawaUNKNOWN Japanese Congenital Diaphragmatic Hernia Study Group
Jul 31, 2004·Seminars in Perinatology·Felicia A Ivascu, Ronald B Hirschl
Jul 30, 2005·Seminars in Perinatology·Fernando R Moya, Kevin P Lally
Oct 10, 2003·Clinics in Perinatology·Roman M Sydorak, Michael R Harrison
Sep 17, 2011·Early Human Development·Ramin KholdebarinRichard Keijzer
Nov 9, 2016·Pediatric Surgery International·Hiroomi OkuyamaUNKNOWN Japanese CDH study group
Jul 20, 2007·Journal of Perinatology : Official Journal of the California Perinatal Association·J W LoganC M Cotten
Dec 2, 2017·Acta Paediatrica·L StormeUNKNOWN French Reference Center for Rare Disease «Congenital Diaphragmatic Hernia»
Feb 8, 2006·The Journal of Veterinary Medical Science·Ken OkabayashiAtsuhiko Hasegawa
Jun 3, 2006·Environmental Monitoring and Assessment·Ching-Liang ChenHung-Yuan Fang
May 25, 2004·Pediatric Surgery International·Hans SkariRagnhild Emblem
Sep 6, 2000·Pediatric Pulmonology·M W Beresford, N J Shaw
Jul 26, 2002·The Cochrane Database of Systematic Reviews·V MoyerK P Lally
Oct 12, 2020·Surgery Today·Masaya YamotoUNKNOWN Japanese Congenital Diaphragmatic Hernia Study Group
Apr 14, 2021·Pediatrics International : Official Journal of the Japan Pediatric Society·Miharu ItoUNKNOWN Japanese Congenital Diaphragmatic Hernia Study Group

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