Is duration of illness really influencing outcome in major psychoses?

Nordic Journal of Psychiatry
Alfredo Carlo AltamuraMassimiliano Buoli

Abstract

An increasing number of studies identifies the duration of illness (DI) as an important predictor of outcome in patients affected by major psychoses (MP). The aim of the present paper was to revise medical literature about DI and its effects on MP, focusing in particular on the relationship between DI and outcome with particular reference to treatment response, suicidal risk, cognitive impairment and social functioning. A search in the main database sources has been performed to obtain a comprehensive overview. Studies with different methodologies (open and double-blinded) have been included, while papers considering other variables such as duration of untreated episode/illness were excluded. MP included the diagnoses of schizophrenia, bipolar disorder and major depressive disorder. Available data show that DI influences treatment response, suicidal risk and loss of social functioning in schizophrenic patients, while results are more controversial with regard to cognitive impairment. In bipolar disorder, a long DI has been associated with less treatment response, more suicidal risk and cognitive impairment, but more data are needed to draw definitive conclusions. Finally, studies, regarding DI of illness and its predictive valu...Continue Reading

References

Jul 1, 1977·The British Journal of Psychiatry : the Journal of Mental Science·W H Lo, T Lo
Sep 1, 1992·The American Journal of Psychiatry·A D LoebelS R Szymanski
Jun 1, 1992·The Australian and New Zealand Journal of Psychiatry·W F Tsoi, E H Kua
May 1, 1991·Acta Psychiatrica Scandinavica·H Jonsson, A K Nyman
Sep 1, 1991·Acta Psychiatrica Scandinavica·W F Tsoi, K E Wong
Jan 1, 1990·Progress in Neuro-psychopharmacology & Biological Psychiatry·C A AltamuraF De Novellis
Aug 1, 1990·Archives of General Psychiatry·D F LevinsonP Silver
Jan 1, 1990·Clinical Neuropharmacology·S R BareggiA R Moro
May 1, 1989·The British Journal of Psychiatry : the Journal of Mental Science·D Dodwell, D Goldberg
Apr 1, 1989·The British Journal of Psychiatry : the Journal of Mental Science·A VergheseJ K Trivedi
Mar 1, 1985·The British Journal of Psychiatry : the Journal of Mental Science·T KolakowskaB M Mandelbrote
Feb 1, 1986·The British Journal of Psychiatry : the Journal of Mental Science·T J CrowE C Johnstone
Sep 1, 1986·The American Journal of Psychiatry·C J RabinerJ M Kane
Dec 1, 1986·Journal of Clinical Psychopharmacology·H Y MeltzerD J Luchins
Jul 1, 1986·Journal of Affective Disorders·A J Mander
Jul 1, 1988·Journal of Affective Disorders·P P Roy-ByrneA S Rosoff
Jan 1, 1988·Journal of Clinical Epidemiology·T W Foo, T K Hoo
Jan 1, 1984·Progress in Neuro-psychopharmacology & Biological Psychiatry·H ItohK Ichikawa
Dec 1, 1983·The American Journal of Psychiatry·A D PokornyR J Lorimor
Apr 1, 1984·Acta Psychiatrica Scandinavica·H Jonsson, A K Nyman
May 1, 1983·The Journal of Nervous and Mental Disease·L N RosenR R Fieve
Jan 1, 1982·Archives of General Psychiatry·W Coryell, M T Tsuang
May 1, 1995·The American Journal of Psychiatry·D F LevinsonM J Stephanos
Apr 1, 1994·The British Journal of Psychiatry : the Journal of Mental Science·T M HydeJ E Kleinman
Mar 1, 1994·The American Journal of Psychiatry·M Maj
Jun 1, 1994·Archives of General Psychiatry·R HeatonD V Jeste
Apr 1, 1996·The American Journal of Psychiatry·S R SzymanskiR E Gur
Nov 1, 1995·Psychological Medicine·R RamanaP G Surtees
Dec 13, 1995·Journal of Affective Disorders·R A BurnsM T Abou-Saleh
Sep 1, 1996·Archives of General Psychiatry·T I MuellerJ Endicott
Jun 20, 1996·Journal of Affective Disorders·M MajL Magliano
Dec 1, 1996·Psychological Reports·J I TracyR C Josiassen
Dec 24, 1995·Journal of Affective Disorders·B AhrensB Müller-Oerlinghausen
Feb 1, 1997·Journal of the American Academy of Child and Adolescent Psychiatry·I M GoodyerJ Pearson
May 1, 1997·Psychological Medicine·L Mynors-Wallis, D Gath
Jan 1, 1997·European Archives of Psychiatry and Clinical Neuroscience·P R MenezesA H Mann
Jan 1, 1996·Harvard Review of Psychiatry·J T Coyle
Mar 10, 1998·The Journal of Clinical Psychiatry·C A ZarateA Madrid
Jun 3, 1998·Journal of Affective Disorders·L V KessingP B Mortensen
Oct 28, 1998·Schizophrenia Research·M J CuestaA Zarzuela
Feb 2, 2000·European Archives of Psychiatry and Clinical Neuroscience·F A Henn, D F Braus
May 19, 2000·The Journal of Clinical Psychiatry·C A ZarateJ Zapatel

❮ Previous
Next ❯

Citations

Jan 1, 2016·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Ching-Hua LinHsien-Yuan Lane
Jun 15, 2016·Human Psychopharmacology·Massimiliano BuoliWiepke Cahn
Sep 18, 2015·Journal of Geriatric Psychiatry and Neurology·Massimiliano BuoliAlfredo Carlo Altamura
Jul 18, 2017·World Journal of Psychiatry·Silvia GrassiMassimiliano Buoli
Apr 16, 2018·Alcoholism, Clinical and Experimental Research·Sheng-Yu LeeRu-Band Lu
Jan 20, 2019·The Australian and New Zealand Journal of Psychiatry·Alfredo Carlo AltamuraUNKNOWN ISBD Italian Chapter Epidemiological Group
Sep 25, 2019·European Psychiatry : the Journal of the Association of European Psychiatrists·Massimiliano BuoliUNKNOWN ISBD Italian Chapter Epidemiologic Group
Aug 20, 2019·European Archives of Psychiatry and Clinical Neuroscience·Silvia TabanoMassimiliano Buoli
Feb 9, 2017·International Clinical Psychopharmacology·Cheng-Chung ChenMing-Chao Chen
Oct 13, 2017·The International Journal of Neuropsychopharmacology·Oloruntoba J OlubokaPierre Blier
Oct 16, 2020·Early Intervention in Psychiatry·Massimiliano BuoliUNKNOWN ISBD Italian Chapter Epidemiologic Group
Oct 16, 2021·European Archives of Psychiatry and Clinical Neuroscience·Massimiliano BuoliUNKNOWN ISBD Italian Chapter Epidemiologic Group

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bipolar Disorder

Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.