Is DVT prophylaxis overemphasized? A randomized prospective study

The Journal of Surgical Research
M A KosirM Dahn

Abstract

This study was designed to prospectively evaluate a previously published prognostic index for predicting deep venous thrombosis (DVT) in general surgical patients with conventional prophylaxis. Patients undergoing procedures of at least 1 hr duration (abdominal, thoracic, head and neck, inguinal) requiring general or spinal anesthetic were prospectively randomized into the following groups: Group 1, sequential pneumatic compression devices during surgery and 2 days postoperatively; Group 2, subcutaneous heparin (5000 U q 12 hr) starting 1 hr before surgery and for 7 days postop; Group 3, control group. All patients underwent duplex evaluation of bilateral lower extremity deep venous systems preoperatively and on postoperative Days 1, 3, and 30. In addition, a previously developed predictive DVT incidence indicator, the prognostic index (PI), was calculated for each patient. A total of 137 patients were entered into the study with 29 removed for patient/staff reasons. There were no differences in PI among the three groups at the 0.05 level (ANOVA). The distribution of risk factors for DVT including increased age, body size, hemoglobin (Hb), and colorectal procedures were distributed evenly among the groups. Additional factors su...Continue Reading

Citations

Aug 13, 2010·Theoretical Biology & Medical Modelling·David K CundiffJohn C Pezzullo
Jun 28, 2013·ANZ Journal of Surgery·Raaj ChandraJames Moore
Nov 1, 2001·The Cochrane Database of Systematic Reviews·P Wille-JørgensenL Borly
Feb 22, 2005·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·L BorlyM S Rasmussen
Feb 18, 2004·International Journal of Circumpolar Health·Ted Rosenzweig
Oct 30, 2003·The Cochrane Database of Systematic Reviews·P Wille-JørgensenL Borly

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