Is e-cigarette use in non-smoking young adults associated with later smoking? A systematic review and meta-analysis.

Tobacco Control
Jasmine N KhoujaMarcus R Munafò

Abstract

The aim of this review was to investigate whether e-cigarette use compared with non-use in young non-smokers is associated with subsequent cigarette smoking. PubMed, Embase, Web of Science, Wiley Cochrane Library databases, and the 2018 Society for Research on Nicotine and Tobacco and Society for Behavioural Medicine conference abstracts. All studies of young people (up to age 30 years) with a measure of e-cigarette use prior to smoking and an outcome measure of smoking where an OR could be calculated were included (excluding reviews and animal studies). Independent extraction was completed by multiple authors using a preprepared extraction form. Of 9199 results, 17 studies were included in the meta-analysis. There was strong evidence for an association between e-cigarette use among non-smokers and later smoking (OR: 4.59, 95% CI: 3.60 to 5.85) when the results were meta-analysed in a random-effects model. However, there was high heterogeneity (I2 =88%). Although the association between e-cigarette use among non-smokers and subsequent smoking appears strong, the available evidence is limited by the reliance on self-report measures of smoking history without biochemical verification. None of the studies included negative control...Continue Reading

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Citations

Jan 16, 2021·Tobacco Use Insights·Navitha JayakumarRobert Schwartz
Jan 21, 2021·International Journal of Environmental Research and Public Health·Andrea K BowePaul Kavanagh
Feb 17, 2021·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Aaron BrounKelvin Choi
Apr 20, 2021·Preventive Medicine Reports·Mohammed Al-Hamdani, Eden Manly
May 27, 2021·Journal of the American Pharmacists Association : JAPhA·Aminat TeribaUche Anadu Ndefo
Jun 11, 2021·The American Journal on Addictions·Alan C SwannThomas R Kosten
Feb 26, 2021·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Lin LiAnn McNeill
May 18, 2021·JAMA Internal Medicine·Anand R Habib, Mitchell H Katz
Aug 20, 2021·American Journal of Public Health·David J K BalfourRobert West
Aug 26, 2021·JAMA Network Open·Ruoyan SunKenneth E Warner
Aug 28, 2021·Journal of Personalized Medicine·Serafeim-Chrysovalantis KotoulasAthanasia Pataka
Aug 13, 2021·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Ann-Kathrin SeidelReiner Hanewinkel
Aug 27, 2021·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Benjamin R Chand, Hassan Hosseinzadeh

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