Is Elective Soft Tissue Hand Surgery Associated with Periprosthetic Joint Infection after Total Joint Arthroplasty?

Clinical Orthopaedics and Related Research
Kevin LiRobin N Kamal

Abstract

Although current guidelines do not recommend the routine use of surgical antibiotic prophylaxis to reduce the risk of surgical site infection following clean, soft tissue hand surgery, antibiotics are nevertheless often used in patients with an existing joint prosthesis to prevent periprosthetic joint infection (PJI), despite little data to support this practice. (1) Is clean, soft tissue hand surgery after THA or TKA associated with PJI risk? (2) Does surgical antibiotic prophylaxis before hand surgery decrease PJI risk in patients with recent THA or TKA? We assessed all patients who underwent THA or TKA between January 2007 and December 2015 by retrospective analysis of the IBM® MarketScan® Databases, which provide a longitudinal view of all healthcare services used by a nationwide sample of millions of patients under commercial and supplemental Medicare insurance coverage-particularly advantageous given the relatively low frequency of hand surgery after THA/TKA and of subsequent PJI. The initial search yielded 940,861 patients, from which 509,896 were excluded for not meeting continuous enrollment criteria, having a diagnosis of PJI before the observation period, or having another arthroplasty procedure before or during the ...Continue Reading

References

Nov 25, 1998·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·E F BerbariD R Osmon
Sep 3, 2004·The Journal of Bone and Joint Surgery. American Volume·Jeffrey N KatzElena Losina
Dec 22, 2006·American Journal of Epidemiology·Eric Vittinghoff, Charles E McCulloch
Apr 1, 2008·Gastrointestinal Endoscopy·Subhas BanerjeeLeslie E Stewart
Jun 26, 2009·Clinical Orthopaedics and Related Research·Kevin J BozicDaniel J Berry
Aug 12, 2009·Clinical Orthopaedics and Related Research·Steven M KurtzJavad Parvizi
Dec 10, 2009·Acta Orthopaedica·Håvard DaleLars B Engesaeter
Jun 24, 2010·The Journal of Arthroplasty·Kevin J BozicDaniel J Berry
Dec 2, 2011·The Journal of the American Dental Association·Daniel D SkaarBryan S Michalowicz
Dec 17, 2011·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Michael S CalderwoodUNKNOWN CDC Prevention Epicenters Program
Jun 14, 2012·Orthopedics·Rick TostiAsif M Ilyas
Jul 10, 2012·Clinical Orthopaedics and Related Research·Max GreenkyJavad Parvizi
Dec 12, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Douglas R OsmonUNKNOWN Infectious Diseases Society of America
May 25, 2013·The Journal of Arthroplasty·Kevin J BozicCraig J Della Valle
Apr 4, 2014·Clinical Microbiology Reviews·Aaron J Tande, Robin Patel
Jul 3, 2015·Lancet·Bhaveen H KapadiaMichael A Mont
Feb 15, 2017·The Journal of the American Academy of Orthopaedic Surgeons·Wenjing ZengJohn Elfar
Feb 6, 2018·The Journal of Hand Surgery·Shepard P JohnsonJennifer F Waljee

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