Is erectile dysfunction a sentinel symptom for cardiovascular autonomic neuropathy in patients with type 2 diabetes?

Andrologia
M DebonoJ Vassallo

Abstract

The study investigated whether there is a significant association between erectile dysfunction (ED) secondary to autonomic failure, and cardiovascular autonomic neuropathy (CAN) in male patients suffering from type 2 diabetes. Twenty-two patients suffering from type 2 diabetes were recruited for this study after satisfying the stringent exclusion criteria used in the first stage. They had no evidence of overt cardiovascular disease, hypertension, neurological, renal or thyroid disease. Each subject was assessed for ED and CAN using standardized tests. Six patients were suffering from CAN while 10 patients were suffering from ED. There was no significant association between CAN and autonomic ED (P = 1). Three patients with normal erectile function had CAN, whilst three patients with ED had CAN. Further analysis demonstrates a significant increase in association between ED and CAN with age (P = 0.036). These results show that ED secondary to autonomic neuropathy is not significantly associated with CAN in this specific group of patients. Nonetheless, the study reveals that ED is a sentinel symptom for future development of CAN.

References

Jan 1, 1989·Diabetic Medicine : a Journal of the British Diabetic Association·H A NeilJ I Mann
Dec 15, 1973·Lancet·D J EwingB F Clarke
Sep 1, 1984·Diabetes Care·M A PfeiferD Porte
Jun 1, 1983·Acta Psychiatrica Scandinavica·A S Zigmond, R P Snaith
Mar 20, 2003·Current Diabetes Reports·D Ziegler
Apr 30, 2003·Diabetes Care·Aaron I VinikRoy Freeman
Nov 11, 2003·Comprehensive Therapy·Aaron I Vinik, Anahit Mehrabyan
Apr 17, 2004·Seminars in Neurology·Aaron I VinikTomris Erbas
Jul 20, 2005·Archives of Andrology·I KelesE Batislam
Oct 18, 2005·Journal of the American College of Cardiology·Emilio ChiurliaMaria G Modena

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Citations

Dec 10, 2015·The Journal of Sexual Medicine·Biljana MusickiArthur L Burnett
Oct 27, 2015·Reviews in Endocrine & Metabolic Disorders·Giuseppe DefeudisPaolo Pozzilli
Jul 22, 2010·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·M Tolga DogruAhmet Haciislamoglu
Oct 22, 2016·Current Diabetes Reports·Barbara H BraffettAruna V Sarma

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