PMID: 9183546Apr 1, 1997Paper

Is familial combined hyperlipidaemia a genetic disorder of adipose tissue?

Current Opinion in Lipidology
P Arner

Abstract

Familial combined hyperlipidaemia is a common cause of coronary heart disease. Its aetiology is heterogeneous. The genetic and metabolic basis of the disorder has not yet been defined. This review discusses the putative role of adipose tissue in the pathogenesis of familial combined hyperlipidaemia. It is possible that mutations in genes regulating the turnover of lipids in fat cells are involved in the aetiology.

Citations

Dec 21, 2000·Current Atherosclerosis Reports·P Pajukanta, K V Porkka
Sep 29, 2011·Nature·Peter ArnerKirsty L Spalding
Apr 16, 2014·Trends in Endocrinology and Metabolism : TEM·Peter Arner, Dominique Langin
Dec 20, 2011·Biochimica Et Biophysica Acta·Kimberly A EdgelRenée C Leboeuf
Nov 29, 2005·Best Practice & Research. Clinical Endocrinology & Metabolism·Peter Arner
Sep 28, 2005·Clinica Chimica Acta; International Journal of Clinical Chemistry·Shui-Ping ZhaoJie Wu
Oct 24, 1998·Endocrinology and Metabolism Clinics of North America·J Davignon, J Genest
Feb 28, 2001·Diabetes, Obesity & Metabolism·J F AscasoR Carmena
Jan 15, 2013·Journal of the American Heart Association·Keith FraynPeter Arner
Nov 13, 1998·Arteriosclerosis, Thrombosis, and Vascular Biology·E TahvanainenC Ehnholm
Sep 23, 2003·Arteriosclerosis, Thrombosis, and Vascular Biology·Rossitza P NaoumovaCarol C Shoulders
Aug 20, 2008·British Journal of Haematology·Saskia Middeldorp, Astrid van Hylckama Vlieg
Jun 30, 1998·Current Opinion in Lipidology·J de Graaf, A F Stalenhoef
Jan 5, 2012·PloS One·Georgios AthanasiadisJosé Manuel Soria
Feb 11, 2012·International Journal of Laboratory Hematology·P C CooperR M Maclean
Jul 11, 2000·British Journal of Haematology·R J OldsC P Geary

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.