Is fetal magnetic resonance imaging indicated when ultrasound isolated mild ventriculomegaly is present in pregnancies with no risk factors?

Prenatal Diagnosis
Cecilia ParazziniFabio Triulzi

Abstract

Ventriculomegaly (VM) is the most common brain anomaly in prenatal ultrasound (US) diagnosis. There is a general trend to perform fetal magnetic resonance imaging (MRI) when VM is severe (greater than 15 mm) and/or it is not isolated. The role of MRI is debated when VM is borderline (between 10 and 15 mm) and isolated. Some authors have subdivided borderline VM into mild (10 to 12 mm) and moderate (>12 to 15 mm). The aim of the study was to evaluate the role of MR in the imaging protocol of fetal cases characterized by mild isolated VM and no risk factors. As a retrospective study, 179 fetal MRI exams (mean gestational age: 26 weeks), performed for mild, isolated VM on US, were analyzed to search additional or different findings with respect to ultrasound. The potential impact of MRI results on prenatal counselling is described. In 49/179 cases, MRI and US results differed, but only in two of these cases did MRI studies provide clinically consistent additional information. In 130/179 cases, MRI confirmed US findings. In this extremely selected group of fetuses with isolated, mild VM and no risk factors, MRI may not be indicated in the prenatal imaging protocol.

References

Mar 1, 1991·American Journal of Obstetrics and Gynecology·B BromleyB R Benacerraf
Jan 1, 1990·Fetal Diagnosis and Therapy·K H NicolaidesC Gosden
Mar 21, 1998·American Journal of Obstetrics and Gynecology·P VerganiA Ghidini
Jan 7, 2000·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·G PiluL Bovicelli
May 30, 2002·Radiology·Deborah LevinePatrick D Barnes
Aug 16, 2003·Radiology·Deborah LevineTejas S Mehta
Apr 22, 2004·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Dan V ValskySimcha Yagel
Dec 3, 2005·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·C Garel, C Alberti
Jul 11, 2006·BJOG : an International Journal of Obstetrics and Gynaecology·L J SalomonC Garel
Oct 25, 2007·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Beryl R BenacerrafDeborah Levine
Feb 3, 2009·Prenatal Diagnosis·Pietro GagliotiTullia Todros
Apr 24, 2010·Radiology·Chiara DonedaFabio Triulzi

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Citations

Jan 12, 2013·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Mehmet Serdar KutukMustafa Tas
Jul 26, 2014·Current Problems in Diagnostic Radiology·Matthew R Plunk, Teresa Chapman
Nov 26, 2015·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Martine van DoornEva Pajkrt
Mar 14, 2014·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·G PaganiF Prefumo
Apr 19, 2016·Bioscience Trends·Nan ChuBin Zhang
Feb 27, 2015·Journal of Perinatal Medicine·Vincenzo D'Addario
Mar 3, 2015·Journal of Medical Imaging and Radiation Oncology·Tejaswi KandulaStacy K Goergen
May 13, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Katrin TomicGwendolin Manegold-Brauer
May 17, 2017·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Jared M PisapiaGregory G Heuer
Aug 31, 2018·Journal of Perinatology : Official Journal of the California Perinatal Association·Jenna A KatzSusan R Hintz
Dec 15, 2018·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D Di MascioF D'Antonio
Mar 26, 2019·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D PaladiniA Rossi
Aug 11, 2020·American Journal of Perinatology·Marwan Ma'ayehKara M Rood
Mar 19, 2016·AJNR. American Journal of Neuroradiology·M Brossard-RacineC Limperopoulos
Dec 10, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Anju BhatiaGeorge Seow Heong Yeo
Jul 10, 2021·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Sureyya Saridas DemirSabahattin Altunyurt

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