Is ganglionated plexus ablation effective for treating atrial fibrillation?

Surgery Today
Michiko WatanabeGoro Matsumiya

Abstract

Very few studies have investigated the efficacy of ganglionated plexus ablation during the conventional maze procedure. In this study, we sought to evaluate its additive effect in reducing recurrent atrial fibrillation after concomitant maze surgery. A retrospective study was conducted of 79 patients who underwent Cox maze IV concomitantly with open-heart surgery with (GP group) or without (Maze group) ganglionated plexus mapping. All active ganglionated plexuses were ablated. The two groups were compared and their follow-up data were analyzed. Active ganglionated plexuses were found in 81% of patients who underwent ganglionated plexus mapping. The rates of freedom from atrial fibrillation at 1 year in the GP and Maze groups were 77 and 75%, respectively. The cumulative freedom from atrial fibrillation at follow-up (27.7 ± 17.3 months) was comparable in the two groups (p = 0.427). A multivariate analysis revealed that persistent atrial fibrillation for more than 90 months was an independent predictor of recurrent atrial fibrillation. Ganglionated plexus ablation with Cox maze IV did not reduce the incidence of recurrent atrial fibrillation in comparison to Maze alone.

References

Apr 25, 2003·Pacing and Clinical Electrophysiology : PACE·Stefan LönnerholmCarina Blomström-Lundqvist
Sep 1, 2005·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Benjamin J ScherlagRalph Lazzara
May 3, 2006·Pacing and Clinical Electrophysiology : PACE·Jay ChenMohamed H Hamdan
Aug 12, 2008·The Journal of Thoracic and Cardiovascular Surgery·Francesco OnoratiAttilio Renzulli
Sep 11, 2009·The Journal of Thoracic and Cardiovascular Surgery·Shun-ichiro SakamotoRalph J Damiano
Feb 23, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Evgeny PokushalovDemosthenes G Katritsis
Dec 22, 2010·The Annals of Thoracic Surgery·Adam L WareHartzell V Schaff
Aug 27, 2013·Journal of the American College of Cardiology·Demosthenes G KatritsisJohn P A Ioannidis
Mar 26, 2014·Circulation Journal : Official Journal of the Japanese Circulation Society·Yuji MurakawaUNKNOWN Japanese Heart Rhythm Society Members
May 20, 2015·International Journal of Cardiology·Sandro GelsominoJos G Maessen

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Citations

Jul 29, 2020·General Thoracic and Cardiovascular Surgery·Kazuo YamanakaMasatoshi Fujita

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