Is Hartmann's the solution?

Anaesthesia
S A White, D R Goldhill

Abstract

As Hartmann's solution is commonly used by anaesthetists, we surveyed a group of Part III FRCA candidates to establish their knowledge of its constituents and the purpose and metabolism of the lactate in solution. Of the 82 candidates surveyed only three (4%) accurately recorded the electrolytes and their concentrations in Hartmann's solution. Lactate was stated to be a source of bicarbonate by 52 (63%) and a source of glucose by 17 (21%). The descriptions of lactate metabolism were largely imprecise, none was complete and 24 (29%) of candidates offered no explanation. The constituents of Hartmann's solution and their concentrations are designed to match those of plasma, reducing ion and fluid shifts postinfusion. The lactate in Hartmann's solution is metabolised by both oxidation and gluconeogenesis, predominantly in the liver, and bicarbonate is generated by both processes over 1-2 h.

Citations

Mar 2, 2002·Anaesthesia·D G MaloneyR S Vaughan
Feb 4, 2010·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Pablo G EulmesekianDesmond Bohn
Feb 18, 2011·American Journal of Therapeutics·Akhilesh Kumar TiwariGrace Valson
Feb 26, 2000·Anesthesiology·D A StoryR Bellomo
Nov 11, 2008·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Desmond Bohn
Jun 10, 2017·International Anesthesiology Clinics·Craig S Jabaley, Roman Dudaryk
Feb 26, 2000·Anesthesiology·G B Drummond
Dec 13, 2007·The Journal of Trauma·Cuthbert O SimpkinsBrad Snyder

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