Is helium insufflation superior to carbon dioxide insufflation in bacteremia and bacterial translocation with peritonitis?

Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a
C ErenogluA Batkin

Abstract

To evaluate the effects of CO2 or helium insufflation on bacteremia and bacterial translocation in rats with peritonitis. Forty male Wistar-Albino rats were divided into four groups, each containing 10 rats. The rats in the first group were injected only with E. coli into their peritoneal cavities with no further manipulation. The second group, following E. coli injection, underwent midline laparotomy without manipulation of the viscera for 1 hour. After the injection of E. coli in the third and fourth groups, CO2 and helium pneumoperitoneum, respectively, were maintained for 1 hour under 14 mm Hg pressure. At the end of the sixth hour, tissue samples were taken from the liver, spleen, lung, and mesenteric lymph nodes in order to evaluate bacterial translocation. During the study, blood samples were taken from each rat at 0, 1, 2, 4, and 6 hours to demonstrate bacteremia. There was a significant increase in bacteremia in the CO2 pneumoperitoneum group compared with the laparotomy-only and helium groups at 1 and 2 hours. Although all the blood samples at the fourth hour were positive for E. coli in every rat of all groups, helium was associated with a lower incidence of bacteremia at the sixth hour compared with other groups (P ...Continue Reading

References

Feb 1, 1995·Iowa Medicine : Journal of the Iowa Medical Society·W BowerM Westberg
Jan 1, 1996·Gastrointestinal Endoscopy·T J NeubergerD L Kaminski
Dec 1, 1996·Surgical Endoscopy·M R EvasovichL Treen
Mar 1, 1997·Surgical Endoscopy·C A JacobiJ M Müller
Jul 22, 1999·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·C A JacobiJ M Müller
Nov 11, 1999·Surgical Endoscopy·E G ChekanC J Westcott
Nov 9, 2000·World Journal of Surgery·S J NeuhausG G Jamieson

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Citations

Jul 13, 2004·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Sezein YilmazOzcan Gökçe
Apr 4, 2006·Acta Cirúrgica Brasileira·Irami Araújo FilhoAldo Cunha Medeiros
Aug 31, 2006·Journal of Clinical Gastroenterology·Uwe WeickertJürgen Ferdinand Riemann
Jan 23, 2009·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Fotios-Filippos KarantonisAlkiviadis Kostakis

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