Is high PEEP ventilation strategy safe for acute respiratory distress syndrome after severe traumatic brain injury?

Brain Injury : [BI]
Meiqing LouKe Wang

Abstract

To investigate the safety and efficacy of high positive end-expiratory pressure (PEEP) ventilation strategy for acute respiratory distress syndrome (ARDS) after traumatic brain injury. A case report and discussion based on literature review. This article reports the case of a 17-year-old male patient who developed ARDS after severe traumatic brain injury. PEEP was applied and adjusted to appropriate levels on the basis of information obtained from continuous monitoring of cerebral and systemic haemodynamics. Data from medical charts, surgical notes and radiographic findings were reviewed and analysed. With the application of high PEEP ventilation, the patient survived ARDS following severe traumatic brain injury and achieved a favourable neurological outcome. A titration of PEEP levels from 5-15 cm H₂O in the patient resulted in acceptable changes of cerebral and systemic haemodynamics, including an increase of intracranial pressure (ICP) from 15 to 18 mmHg and a decrease of cerebral perfusion pressure (CPP) from 78 to 72 mmHg. With close monitoring of cerebral and systemic haemodynamics, PEEP can be safely applied and titrated to an optimal level in the management of ARDS following traumatic brain injury.

References

Dec 1, 1992·Journal of Neurosurgery·J PiekM A Foulkes
Oct 1, 1985·Journal of Neurosurgery·K R CooperS C Choi
Apr 1, 1997·Neurosurgery·S L Bratton, R L Davis
May 4, 2000·The New England Journal of Medicine·UNKNOWN Acute Respiratory Distress Syndrome NetworkArthur Wheeler
Sep 8, 2010·Indian Journal of Pediatrics·Sunil SaharanSushil Kumar Kabra

❮ Previous
Next ❯

Citations

Mar 10, 2016·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Jonathan A N FisherCristin G Welle
Oct 28, 2017·Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko·M B NazarenkoK A Popugaev
May 1, 2021·Perfusion·Ismael A Salas De ArmasIgor D Gregoric

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.

Related Papers

European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
Hagen Bernhard HuttnerStefan Schwab
Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Nancy CarneyWorld Federation of Pediatric Intensive and Critical Care Societies
© 2021 Meta ULC. All rights reserved