PMID: 8994991Jan 1, 1997Paper

Is it necessary to retrieve dropped gallstones during laparoscopic cholecystectomy?

Surgical Endoscopy
A ZorluoğluN Güney

Abstract

An experimental study was planned to evaluate the effect of bile alone and bile in combination with gallstones on intraperitoneal adhesion and abscess formation in the peritoneal cavity of the rat. One hundred Sprague-Dawley rats were assigned to ten groups (n: 10). Groups 1-3 received a 1-ml intraperitoneal injection of saline, sterile bile, and infected bile. Groups 4-10 underwent a lower 5-mm midline abdominal incision. In groups 5, 7, and 9, a single gallstone (3-mm diameter) was placed in the right upper quadrant and injected with sterile saline, sterile bile, and infected bile, respectively. In groups 6, 8, and 10, four gallstones (3-mm diameter) were placed in the right upper quadrant together with sterile saline, sterile bile, and infected bile, respectively. Group 4 only underwent a 5-mm midline incision. All animals were sacrificed at the end of 4 weeks and the peritoneal cavity was carefully examined to investigate adhesions and abscess formation. The adhesions were graded according to Nair's gross pathologic grading of adhesions. The Kruskal-Wallis nonparametric test (KW) was used for statistical analysis. No intraabdominal lesions were noted in groups 1-3. The adhesion score was increased by number of stone and inf...Continue Reading

Citations

May 19, 2005·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Gurhan BasMustafa Sahin
May 2, 2001·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·A P KelkarA G Patel
Dec 22, 2007·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Hayrullah DericiEnver Reyhan
Feb 19, 2004·Postgraduate Medical Journal·T Sathesh-KumarR L Blackett
Jul 27, 2006·Digestive Surgery·C S BhatiS R Bramhall
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Jun 4, 2016·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Azadeh Jabbari NooghabiAli Jangjoo
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Mar 12, 2008·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·P HazrahH S Shukla
Aug 3, 2021·Case Reports in Surgery·Aizat DrahmanFrank Sardelic

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