Is it possible for knowledge-based planning to improve intensity modulated radiation therapy plan quality for planners with different planning experiences in left-sided breast cancer patients?

Radiation Oncology
Juanqi WangGongyi Yu

Abstract

Knowledge-based planning (KBP) is a promising technique that can improve plan quality and increase planning efficiency. However, no attempts have been made to extend the domain of KBP for planners with different planning experiences so far. The purpose of this study was to quantify the potential gains for planners with different planning experiences after implementing KBP in intensity modulated radiation therapy (IMRT) plans for left-sided breast cancer patients. The model libraries were populated with 80 expert clinical plans from treated patients who previously received left-sided breast-conserving surgery and IMRT with simultaneously integrated boost. The libraries were created on the RapidPlanTM. 6 planners with different planning experiences (2 beginner planners, 2 junior planners and 2 senior planners) generated manual and KBP optimized plans for additional 10 patients, similar to those included in the model libraries. The plan qualities were compared between manual and KBP plans. All plans were capable of achieving the prescription requirement. There were almost no statistically significant differences in terms of the planning target volume (PTV) coverage and dose conformality. It was demonstrated that the doses for most...Continue Reading

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Jul 10, 2018·Journal of Applied Clinical Medical Physics·Meijiao WangYibao Zhang
Aug 4, 2018·The British Journal of Radiology·Mohammad HusseinAndrew Nisbet
Oct 20, 2018·Journal of Applied Clinical Medical Physics·Elizabeth BossartNesrin Dogan
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Jul 8, 2021·Journal of Applied Clinical Medical Physics·Shadab MominXiaofeng Yang
Jun 17, 2018·Practical Radiation Oncology·Mariët J van Duren-KoopmanWilko F Verbakel

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Software Mentioned

Eclipse system TPS )
SPSS
AutoPlanning
Eclipse
Pinnacle
VMAT

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