Is lactate production related to muscular fatigue? A pedagogical proposition using empirical facts

Advances in Physiology Education
Denise Vaz MacedoRodrigo Hohl

Abstract

The cause-effect relationship between lactic acid, acidosis, and muscle fatigue has been established in the literature. However, current experiments contradict this premise. Here, we describe an experiment developed by first-year university students planned to answer the following questions: 1) Which metabolic pathways of energy metabolism are responsible for meeting the high ATP demand during high-intensity intermittent exercise? 2) Which metabolic pathways are active during the pause, and how do they influence phosphocreatine synthesis? and 3) Is lactate production related to muscular fatigue? Along with these questions, students received a list of materials available for the experiment. In the classroom, they proposed two protocols of eight 30-m sprints at maximum speed, one protocol with pauses of 120 s and the other protocol with pauses of 20 s between sprints. Their performances were analyzed through the velocity registered by photocells. Blood lactate was analyzed before the first sprint and after the eighth sprint. Blood uric acid was analyzed before exercise and 15 and 60 min after exercises. When discussing the data, students concluded that phosphocreatine restoration is time dependent, and this fact influenced the st...Continue Reading

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Citations

Sep 8, 2018·Advances in Physiology Education·Rui Seabra Machado, Pâmela Billig Mello-Carpes
Mar 10, 2011·Advances in Physiology Education·Piero L Ipata
Nov 15, 2011·Journal of Strength and Conditioning Research·Peter C DourisVeronica Southard

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