Is life impossible? Information, sex, and the origin of complex organisms

Evolution; International Journal of Organic Evolution
Joel R Peck, David Waxman

Abstract

The earliest organisms are thought to have had high mutation rates. It has been asserted that these high mutation rates would have severely limited the information content of early genomes. This has led to a well-known “paradox” because, in contemporary organisms, the mechanisms that suppress mutations are quite complex and a substantial amount of information is required to construct these mechanisms. The paradox arises because it is not clear how efficient error-suppressing mechanisms could have evolved, and thus allowed the evolution of complex organisms, at a time when mutation rates were too high to permit the maintenance of very substantial amounts of information within genomes. Here, we use concepts from the formal theory of information to calculate the amount of genomic information that can be maintained. We identify conditions under which much higher levels of genomic information can be maintained than previously considered possible among origin-of-life researchers. In particular, we find that the highest levels of information are maintained when many genotypes produce identical phenotypes, and when reproduction occasionally involves recombination between multiple parental genomes. There is a good reason to believe that...Continue Reading

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Citations

May 17, 2011·Trends in Ecology & Evolution·Harold P de Vladar, Nicholas H Barton
Apr 7, 2015·Journal of Theoretical Biology·Marcus A M de AguiarAyana B Martins
Jun 4, 2019·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Kristin M Lee, Graham Coop
Dec 18, 2013·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·David B Saakian, Chin-Kun Hu

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