PMID: 9442983Jan 1, 1997Paper

Is life stress more likely to provoke depressive episodes in women than in men?

Depression and Anxiety
J T SherrillD J Kupfer

Abstract

One of the most consistent findings in psychiatric research is that rates of major depression are at least twofold higher among women than among men. Although there is considerable agreement in the literature that life events play a role in producing, triggering, or maintaining episodes of depression, less is known about the relationship among gender, life events, and depression. In the present study, we compared the rates, focus ("interpersonal" vs. "non-interpersonal"), and timing of stressful life experiences reported in rigorous interviews of male and female patients with unipolar recurrent depression and nondepressed contrast subjects. Consistent with hypotheses, female patients were more likely to experience stressful life experiences than their male counterparts; rates of stressful life experiences did not differ between female and male controls. Unexpectedly, rates of interpersonal stress did not differ among males and females regardless of patient or control status. We also found no significant differences in the timing of pre-onset events: stressful events were generally concentrated in the period immediately preceding onset for both men and women. Thus, although these data suggest that life stress may play a larger r...Continue Reading

Citations

May 30, 2001·Neuroscience and Biobehavioral Reviews·P Palanza
Aug 14, 2003·Psychiatry Research·Douglas E WilliamsonDavid A Brent
Oct 29, 2002·Brain, Behavior, and Immunity·Renaud de Beaurepaire
Aug 23, 2007·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Christina DallaTracey J Shors

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