PMID: 8945024Nov 1, 1996Paper

Is local myocardial contractility related to endocardial acceleration signals detected by a transvenous pacing lead?

Pacing and Clinical Electrophysiology : PACE
M G BongiorniB Garberoglio

Abstract

The availability of sensors monitoring cardiac function parameters may offer many interesting new applications in cardiac pacing. A microaccelerometer sensor (BEST, Biomechanical Endocardial Sorin Transducer) located at the tip of a pacing lead (PL) has been developed by Sorin Biomedica. The signal detected by the accelerometer, peak endocardial acceleration (PEA), was shown to reflect cardiac contractility and to be related to the dP/dt signal. Whether the PEA detected by the BEST sensor in different cardiac locations is the expression of local acceleration forces or reflects the whole heart contractility has not yet been demonstrated in humans. Endocardial acceleration and PEA were evaluated in five patients (4 males, 1 female, mean age 68 years) who underwent cardiac catheterization. Sinus rhythm was present in four patients and chronic atrial fibrillation was present in one. The BEST PL was introduced through the left subclavian vein and PEA signals were recorded: (1) at the apex of the right ventricle (RV), (2) within the coronary sinus (CS), (3) at the right atrial appendage (RAA), and (4) floating in the right atrium. The PEA signals were recorded simultaneously with surface ECG, intracardiac electrograms, and RV pressur...Continue Reading

References

Sep 1, 1991·Pacing and Clinical Electrophysiology : PACE·H J WortelR Van Mechelen
Nov 1, 1988·Pacing and Clinical Electrophysiology : PACE·R Chirife
Aug 1, 1994·Pacing and Clinical Electrophysiology : PACE·G N KayV J Plumb

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Citations

Mar 12, 2008·Herzschrittmachertherapie & Elektrophysiologie·A KloppeM Zarse
Nov 30, 2013·Journal of Healthcare Engineering·Stefania SacchiLuigi Padeletti
Dec 9, 2015·Pacing and Clinical Electrophysiology : PACE·Stefania SacchiLuigi Padeletti
Mar 11, 2009·Pacing and Clinical Electrophysiology : PACE·Daniel GrasPhilippe Mabo
Oct 16, 2010·Journal of Cardiovascular Electrophysiology·Pierre BordacharPierre Dos Santos
Feb 7, 2013·Journal of Cardiovascular Electrophysiology·Sandro BrusichBozidar Ferek-Petric
May 4, 2011·IEEE Transactions on Bio-medical Engineering·Danko TomasicAgostino P Accardo
Mar 10, 2000·Cardiology Clinics·S K Leung, C P Lau
Nov 16, 2010·Journal of Cardiovascular Electrophysiology·Michael O Sweeney

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