PMID: 9169818Mar 15, 1997Paper

Is machine energy (4-8 MV) associated with outcome for stage I-II breast cancer patients?

International Journal of Radiation Oncology, Biology, Physics
J M MonsonJ R Harris

Abstract

To assess the relationship between machine energy (4-8 MV) and treatment outcome in patients treated with conservative surgery and radiation therapy. Between 1968 and 1985, 1624 patients were treated for clinical Stage I or II invasive breast cancer. The study population was limited to 1380 patients who underwent complete gross excision and received greater than or equal to 60 Gy to the tumor bed. Of these, 1125 were treated on a 4 MV, 153 on a 6 MV, and 102 on an 8 MV linear accelerator. Patients were selected for treatment on the 8 MV machine based on chest wall separations greater than 24 cm. Of patients treated on the 8 MV, netting was used for 42% and bolus was used for 26%. The median dose with bolus was 14 Gy in seven fractions (range: 2-34.2 Gy). Patients treated on the 8 MV accelerator were older, had a higher percentage of clinical T2 tumors, a higher percentage of pathologically positive nodes, and a lower incidence of extensive intraductal component (EIC). Median follow-up times were 130, 153, and 102 months, respectively, for survivors treated on the 4, 6, and 8 MV machines. We analyzed the site and 5-year crude incidence of first failure by machine energy and found the pattern of first failure site (local, nodal, ...Continue Reading

References

Jul 1, 1977·International Journal of Radiation Oncology, Biology, Physics·G K SvenssonR R Weichselbaum
Jan 1, 1992·International Journal of Radiation Oncology, Biology, Physics·S M PierceJ R Harris
Jan 1, 1992·International Journal of Radiation Oncology, Biology, Physics·A de la RochefordièreJ R Harris
Dec 1, 1991·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·R Valdagni, C Italia
Jul 1, 1991·International Journal of Radiation Oncology, Biology, Physics·T I LingosJ R Harris
Jan 1, 1990·Journal of the American Academy of Dermatology·D P LookingbillF M Sexton
Dec 1, 1989·International Journal of Radiation Oncology, Biology, Physics·L M ChinJ R Harris
Jul 1, 1985·International Journal of Radiation Oncology, Biology, Physics·S J SchnittJ R Harris
May 1, 1987·Medical Physics·B J GerbiF M Khan
Jun 1, 1985·International Journal of Radiation Oncology, Biology, Physics·R D PeznerK R Desai
Sep 1, 1980·Physics in Medicine and Biology·J M GalvinE Cheng
Dec 1, 1983·International Journal of Radiation Oncology, Biology, Physics·D ClarkeR S Cox
Apr 1, 1983·International Journal of Radiation Oncology, Biology, Physics·R L SiddonG K Svensson
Dec 1, 1980·The American Journal of Surgical Pathology·U Wertheim, L Ozzello
Jun 1, 1980·International Journal of Radiation Oncology, Biology, Physics·G K SvenssonM B Levene

❮ Previous
Next ❯

Citations

May 10, 2000·International Journal of Radiation Oncology, Biology, Physics·A GrannM A Hunt
Apr 7, 2000·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·C R RamseyA Oliver
Apr 15, 2003·Journal of the American College of Surgeons·Valerie L StaradubMonica Morrow
Aug 15, 2006·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Indra J DasLawrence J Solin
Jun 30, 1998·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·W SchiesslP Kneschaurek
Oct 27, 2021·International Journal of Radiation Oncology, Biology, Physics·Alan NicholPauline Truong

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

International Journal of Radiation Oncology, Biology, Physics
T E Merchant, B McCormick
Surgical Endoscopy
D MaguireO J McAnena
International Journal of Radiation Oncology, Biology, Physics
G C Bentel, L B Marks
International Journal of Radiation Oncology, Biology, Physics
A de la RochefordièreJ R Harris
International Journal of Radiation Oncology, Biology, Physics
I A OlivottoJ R Harris
© 2021 Meta ULC. All rights reserved