PMID: 591976Oct 1, 1977

Is malignant hyperpyrexia muscle denervated?

Journal of Neurology, Neurosurgery, and Psychiatry
R F Moulds


To test the hypothesis that human muscular dystrophies may be secondary to denervation, the responses in vitro of muscle in human malignant hyperpyrexia to electrical and pharmacological stimuli have been compared with those of the denervated mouse soleus muscle. The results suggest that the muscle abnormality in malignant hyperpyrexia is different from that produced by denervation. This must cast doubt on the concept that other human muscular dystrophies are secondary to denervation.


Feb 12, 1972·Lancet·J O KingP W Zapf
Nov 1, 1968·The Journal of General Physiology·A Weber
May 1, 1974·Clinical and Experimental Pharmacology & Physiology·R F Moulds, M A Denborough
May 4, 1974·British Medical Journal·R F Moulds, M A Denborough
Apr 1, 1971·Acta Physiologica Scandinavica·P Redfern, S Thesleff


Oct 1, 1984·Muscle & Nerve·G D EngS M Muldoon

Related Concepts

Potentials, Event-Related
Resting Potentials
Muscle Denervation Procedure
Muscular Dystrophy

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