Is mood-incongruent manic psychosis a distinct subtype?

European Archives of Psychiatry and Clinical Neuroscience
C ToniH S Akiskal

Abstract

Despite several research reports on incongruent psychotic features in mania, whether such features define a distinct disorder is unsettled. One hundred and fifty-five inpatients with mania according to DSM-III-R were systematically evaluated in order to collect demographic and clinical information. The symptomatological evaluation was conducted by means of the Comprehensive Psychopathological Rating Scale (CPRS) and the Scale for the Assessment of Positive Symptoms (SAPS). The presence/absence of incongruent psychotic symptoms at the index episode defined two subgroups of patients, whose familial, symptomatological, clinical and course characteristics were compared. Eighty-six (55.5%) patients presented mood-incongruent psychotic features (MIP+). When this group was compared with the remainder of manic patients without such features (MIP-), we found substantial similarities in most demographic, familial and clinical characteristics. Despite these fundamental similarities, 4% of MIP+ vs 0% of MIP- had family history for schizophrenia (p < 0.05). We also observed a longer duration of the current episode, a higher percentage of chronic course, more suicide attempts and hospitalisations in MIP+. Moreover, other than psychotic sympt...Continue Reading

Citations

Feb 5, 2009·European Archives of Psychiatry and Clinical Neuroscience·Andreas MarnerosPeter Brieger
Sep 1, 2004·Journal of Affective Disorders·Philippe ConusPatrick D McGorry
Aug 13, 2004·Journal of Affective Disorders·Joseph F Goldberg, Martin Harrow
Oct 25, 2012·Translational Psychiatry·F S GoesJ B Potash
Jun 15, 2005·Bipolar Disorders·Lakshmi N YathamUNKNOWN Canadian Network for Mood and Anxiety Treatments
Jul 14, 2010·European Psychiatry : the Journal of the Association of European Psychiatrists·J-M AzorinH Akiskal
Oct 12, 2018·Psychological Medicine·Annet H van BergenMarco P M Boks

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