Is multifocal electroretinography an early predictor of glaucoma?

Documenta Ophthalmologica. Advances in Ophthalmology
Haydar GölemezAhmet Özer

Abstract

To investigate the potential use of mfERG as an objective functional test that can express inner and outer retinal changes during the early stages of glaucoma. One hundred and twenty-six eyes of 126 patients were included. There were 30 healthy (Group 1), 28 glaucoma suspect (Group 2), 48 early glaucoma (Group 3), and 20 advanced glaucoma cases (Group 4). After complete ophthalmic examination, Humphrey visual field analysis and mfERG were performed. These examinations were performed three times at 6-month intervals, and only the last examination results were used for the analysis. Visual fields global indices and mfERG implicit time and amplitudes were evaluated and analyzed by ring system (central 5°, 5°-10°, 10°-15° and >15°). One-way ANOVA and ROC curve analysis were used for statistical analysis. There was no statistically (one-way ANOVA) significant differences in patient age between groups (p = 0.126). For all rings, we detected statistically significant differences for the mean implicit time (latency) of the N1, P1, and N2 components between the advanced glaucoma and control subjects and between the advanced glaucoma and glaucoma suspects. The N2 amplitudes were significantly decreased in all rings in the advanced glauco...Continue Reading

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Citations

Dec 31, 2016·Documenta Ophthalmologica. Advances in Ophthalmology·Anthony W Van Alstine, Suresh Viswanathan
Mar 1, 2017·Documenta Ophthalmologica. Advances in Ophthalmology·Laura WilseyBrad Fortune
Dec 7, 2019·Journal of Glaucoma·Cassia SengerJayter S Paula

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